Alberg Anthony J
Hollings Cancer Center and Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA.
Drugs Today (Barc). 2008 Dec;44(12):895-904. doi: 10.1358/dot.2008.44.12.1308898.
Active cigarette smoking causes a broad spectrum of diseases that extend to many different organ systems. Its numerous deleterious health effects, combined with the substantial prevalence of cigarette smoking, make it a major worldwide cause of death. Smoking contributes so heavily to the mortality burden because it is a major cause of vascular disease, cancer and chronic obstructive pulmonary disease. In addition to these diseases, cigarette smoking also causes other respiratory symptoms, adversely affects reproductive outcomes and is a cause of diminished health status. Furthermore, exposure to secondhand smoke is an established cause of coronary heart disease and lung cancer, as well as a host of other adverse health effects. Given that cigarette smoking is such a major threat to global public health, controlling the worldwide epidemic of cigarette smoking would lead to enormous public health benefits. Strategies to control cigarette smoking at the societal level include smoke-free workplace legislation, increasing cigarette taxes and regulating cigarette advertising. On the individual level, preventing the initiation of cigarette smoking among youths is the optimal strategy; in practice, discovering efficacious primary prevention interventions has proven challenging. During the past two decades, major advances have been made in extending the menu of options available to assist dependent smokers in successfully quitting smoking. Successfully combating cigarette smoking requires a broad-based commitment to smoking control from multiple stakeholders, along with a multifaceted strategy that addresses both societal and individual factors.
主动吸烟会引发一系列广泛的疾病,这些疾病会累及许多不同的器官系统。吸烟对健康产生的诸多有害影响,再加上吸烟的高流行率,使其成为全球主要的死亡原因。吸烟对死亡负担的影响如此之大,是因为它是血管疾病、癌症和慢性阻塞性肺疾病的主要病因。除了这些疾病,吸烟还会引发其他呼吸道症状,对生殖结局产生不利影响,并导致健康状况下降。此外,接触二手烟是冠心病和肺癌的既定病因,以及许多其他不良健康影响的原因。鉴于吸烟对全球公共卫生构成如此重大的威胁,控制全球吸烟流行将带来巨大的公共卫生益处。在社会层面控制吸烟的策略包括无烟工作场所立法、提高香烟税和规范香烟广告。在个人层面,防止年轻人开始吸烟是最佳策略;实际上,发现有效的一级预防干预措施已被证明具有挑战性。在过去二十年中,在扩大可用于帮助依赖吸烟者成功戒烟的选择菜单方面取得了重大进展。成功抗击吸烟需要多个利益相关者对控烟做出广泛承诺,以及一项应对社会和个人因素的多方面策略。