用于细胞内测温的亲水荧光纳米凝胶温度计。
Hydrophilic fluorescent nanogel thermometer for intracellular thermometry.
机构信息
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
出版信息
J Am Chem Soc. 2009 Mar 4;131(8):2766-7. doi: 10.1021/ja807714j.
PMID:19199610
Abstract
The first methodology to measure intracellular temperature is described. A highly hydrophilic fluorescent nanogel thermometer developed for this purpose stays in the cytoplasm and emits stronger fluorescence at a higher temperature. Thus, intracellular temperature variations associated with biological processes can be monitored by this novel thermometer with a temperature resolution of better than 0.5 degrees C.
摘要
本文描述了第一种测量细胞内温度的方法。为此目的开发的一种高亲水性荧光纳米凝胶温度计停留在细胞质中，在较高温度下发射更强的荧光。因此，通过这种新型温度计可以监测与生物过程相关的细胞内温度变化，其温度分辨率优于 0.5°C。
Zotero 插件