Boesing F, Patiño J S R, da Silva V R G, Moreira E A M
Post Graduate Program in Nutrition at the Federal University of Santa Catarina, Florianópolis, Brazil.
Obes Rev. 2009 May;10(3):290-7. doi: 10.1111/j.1467-789X.2008.00555.x. Epub 2009 Jan 16.
Obesity is characterized by the abnormal or excessive deposition of fat in the adipose tissue. Its consequences go far beyond adverse metabolic effects on health, causing an increase in oxidative stress that leads not only to endothelial dysfunction but also to negative effects in relation to periodontitis, because of the increase in proinflammatory cytokines. Thus, obesity appears to participate in the multifactorial phenomenon of causality of periodontitis through the increased production of reactive oxygen species. Within this context, this paper aims to highlight, by analysis and description of previous studies, the interface between obesity and periodontitis, with emphasis on oxidative stress and the inflammatory response.
肥胖的特征是脂肪在脂肪组织中异常或过度沉积。其后果远不止对健康产生不良代谢影响，还会导致氧化应激增加，这不仅会导致内皮功能障碍，还会因促炎细胞因子增加而对牙周炎产生负面影响。因此，肥胖似乎通过活性氧生成增加参与了牙周炎因果关系的多因素现象。在此背景下，本文旨在通过对以往研究的分析和描述，突出肥胖与牙周炎之间的联系，重点关注氧化应激和炎症反应。
