家兔乳腺在妊娠和泌乳期间脂肪酸合成、活化及酯化过程中酶的协同变化。

Short V J, Brindley D N, Dils R

Biochem J. 1977 Feb 15;162(2):445-50. doi: 10.1042/bj1620445.

The activities of fatty acid synthetase, acyl-CoA synthetase, glycerol phosphate acyltransferase and phosphatidate phosphatase were measured in the mammary glands of rabbits from day 16 of pregnancy to day 15 of post partum. 2. There were significant correlations between the increases in activities of these enzymes during this period. This was the case whether the activities were expressed per mg of homogenate protein, per g wet wt. of tissue or per total wet weight of the whole glands. The only exception was the lack of correlation between the activities of fatty acid synthetase and of phosphatidate phosphatase per g wet wt. of tissue. 3. These co-ordinate increases are discussed in relation to the changes which occur in fatty acid metabolism in the mammary gland during pregnancy and lactation.

测定了从妊娠第16天到产后第15天兔子乳腺中脂肪酸合成酶、酰基辅酶A合成酶、甘油磷酸酰基转移酶和磷脂酸磷酸酶的活性。2. 在此期间，这些酶活性的增加之间存在显著相关性。无论活性是以每毫克匀浆蛋白、每克组织湿重还是每整个腺体的总湿重来表示，情况都是如此。唯一的例外是每克组织湿重的脂肪酸合成酶和磷脂酸磷酸酶活性之间缺乏相关性。3. 结合妊娠和哺乳期乳腺脂肪酸代谢发生的变化，对这些协同增加进行了讨论。

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

Short V J, Brindley D N, Dils R

Biochem J. 1977 Feb 15;162(2):445-50. doi: 10.1042/bj1620445.

The activities of fatty acid synthetase, acyl-CoA synthetase, glycerol phosphate acyltransferase and phosphatidate phosphatase were measured in the mammary glands of rabbits from day 16 of pregnancy to day 15 of post partum. 2. There were significant correlations between the increases in activities of these enzymes during this period. This was the case whether the activities were expressed per mg of homogenate protein, per g wet wt. of tissue or per total wet weight of the whole glands. The only exception was the lack of correlation between the activities of fatty acid synthetase and of phosphatidate phosphatase per g wet wt. of tissue. 3. These co-ordinate increases are discussed in relation to the changes which occur in fatty acid metabolism in the mammary gland during pregnancy and lactation.

测定了从妊娠第16天到产后第15天兔子乳腺中脂肪酸合成酶、酰基辅酶A合成酶、甘油磷酸酰基转移酶和磷脂酸磷酸酶的活性。2. 在此期间，这些酶活性的增加之间存在显著相关性。无论活性是以每毫克匀浆蛋白、每克组织湿重还是每整个腺体的总湿重来表示，情况都是如此。唯一的例外是每克组织湿重的脂肪酸合成酶和磷脂酸磷酸酶活性之间缺乏相关性。3. 结合妊娠和哺乳期乳腺脂肪酸代谢发生的变化，对这些协同增加进行了讨论。