• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人体视网膜血流的超高速容积断层扫描

Ultra-high-speed volumetric tomography of human retinal blood flow.

作者信息

Schmoll Tilman, Kolbitsch Christoph, Leitgeb Rainer A

机构信息

Center of Biomedial Engineering and Physics, Medical University Vienna, Waehringerstrasse 13, A- 1090 Vienna, Austria .

出版信息

Opt Express. 2009 Mar 2;17(5):4166-76. doi: 10.1364/oe.17.004166.

DOI:10.1364/oe.17.004166
PMID:19259253
Abstract

Applying novel detector development based on CMOS technology to Fourier domain optical coherence tomography we achieve depth profile rates up to 200,000 scans/sec. This speed allows for dramatic improvement for imaging small retinal details, such as photo-receptors and capillaries. We demonstrate the impact of this achievable speed to Doppler tomography and discuss advantages as well as short-comings of high speed 3D Doppler imaging of the human retina. Experimental data of 3D static DFDOCT sets from fovea and nerve head region are shown together with first 4D imaging of retinal capillary flow.

摘要

将基于CMOS技术的新型探测器开发应用于傅里叶域光学相干断层扫描,我们实现了高达200,000次扫描/秒的深度剖面速率。这种速度极大地改善了对视网膜微小细节(如光感受器和毛细血管)的成像。我们展示了这种可实现的速度对多普勒断层扫描的影响,并讨论了人体视网膜高速三维多普勒成像的优点和缺点。展示了来自中央凹和神经头区域的三维静态DFDOCT数据集的实验数据以及视网膜毛细血管血流的首次四维成像。

相似文献

1
Ultra-high-speed volumetric tomography of human retinal blood flow.人体视网膜血流的超高速容积断层扫描
Opt Express. 2009 Mar 2;17(5):4166-76. doi: 10.1364/oe.17.004166.
2
Velocity-resolved 3D retinal microvessel imaging using single-pass flow imaging spectral domain optical coherence tomography.使用单通道血流成像光谱域光学相干断层扫描技术进行速度分辨三维视网膜微血管成像。
Opt Express. 2009 Mar 2;17(5):4177-88. doi: 10.1364/oe.17.004177.
3
Fourier domain mode locking at 1050 nm for ultra-high-speed optical coherence tomography of the human retina at 236,000 axial scans per second.用于人眼视网膜超高速光学相干断层扫描的1050纳米傅里叶域锁模,每秒236,000次轴向扫描。
Opt Lett. 2007 Jul 15;32(14):2049-51. doi: 10.1364/ol.32.002049.
4
Three-dimensional quantitative imaging of retinal and choroidal blood flow velocity using joint Spectral and Time domain Optical Coherence Tomography.使用联合光谱和时域光学相干断层扫描技术对视网膜和脉络膜血流速度进行三维定量成像。
Opt Express. 2009 Jun 22;17(13):10584-98. doi: 10.1364/oe.17.010584.
5
Ultra-high speed and ultra-high resolution spectral-domain optical coherence tomography and optical Doppler tomography in ophthalmology.眼科中的超高速和超高分辨率光谱域光学相干断层扫描及光学多普勒断层扫描
Bull Soc Belge Ophtalmol. 2006(302):123-32.
6
Measurement of absolute blood flow velocity and blood flow in the human retina by dual-beam bidirectional Doppler fourier-domain optical coherence tomography.双光束双向多普勒傅里叶域光相干断层扫描测量人视网膜的绝对血流速度和血流。
Invest Ophthalmol Vis Sci. 2012 Sep 12;53(10):6062-71. doi: 10.1167/iovs.12-9514.
7
Retinal blood flow detection in diabetic patients by Doppler Fourier domain optical coherence tomography.通过多普勒傅里叶域光学相干断层扫描检测糖尿病患者的视网膜血流
Opt Express. 2009 Mar 2;17(5):4061-73. doi: 10.1364/oe.17.004061.
8
In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography.通过傅里叶域多普勒光学相干断层扫描术进行活体视网膜总血流量测量。
J Biomed Opt. 2007 Jul-Aug;12(4):041215. doi: 10.1117/1.2772871.
9
Impact of enhanced resolution, speed and penetration on three-dimensional retinal optical coherence tomography.分辨率、速度和穿透深度增强对三维视网膜光学相干断层扫描的影响
Opt Express. 2009 Mar 2;17(5):4134-50. doi: 10.1364/oe.17.004134.
10
Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography.使用超高分辨率多普勒光学相干血管造影术进行三维血管几何形状测定的定量视网膜血流测量。
Opt Lett. 2008 Apr 15;33(8):836-8. doi: 10.1364/ol.33.000836.

引用本文的文献

1
Automated chick gender determination using optical coherence tomography and deep learning.利用光学相干断层扫描和深度学习实现鸡的性别自动判定
Poult Sci. 2025 May;104(5):105033. doi: 10.1016/j.psj.2025.105033. Epub 2025 Mar 15.
2
250 kHz, 1.5 µm resolution SD-OCT for cellular imaging of the human cornea.用于人眼角膜细胞成像的250千赫兹、分辨率为1.5微米的频域光学相干断层扫描技术
Biomed Opt Express. 2018 Nov 29;9(12):6569-6583. doi: 10.1364/BOE.9.006569. eCollection 2018 Dec 1.
3
Doppler OCT clutter rejection using variance minimization and offset extrapolation.
使用方差最小化和偏移外推法的多普勒光学相干断层扫描杂波抑制
Biomed Opt Express. 2018 Oct 10;9(11):5340-5352. doi: 10.1364/BOE.9.005340. eCollection 2018 Nov 1.
4
Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye.1060纳米紧凑型无运动伪像扫频源光学相干断层扫描血管造影术,支持后眼的宽视野和自适应光学成像模式。
Biomed Opt Express. 2018 Mar 26;9(4):1871-1892. doi: 10.1364/BOE.9.001871. eCollection 2018 Apr 1.
5
Holographic line field en-face OCT with digital adaptive optics in the retina .视网膜中采用数字自适应光学技术的全息线场共焦光学相干断层扫描技术
Biomed Opt Express. 2018 Jan 8;9(2):472-485. doi: 10.1364/BOE.9.000472. eCollection 2018 Feb 1.
6
cellular-resolution retinal imaging in infants and children using an ultracompact handheld probe.使用超紧凑型手持探头对婴幼儿进行细胞分辨率视网膜成像。
Nat Photonics. 2016;10:580-584. doi: 10.1038/nphoton.2016.141. Epub 2016 Aug 1.
7
imaging of the palisades of Vogt and the limbal crypts with sub-micrometer axial resolution optical coherence tomography.采用具有亚微米轴向分辨率的光学相干断层扫描对沃格特栅栏和角膜缘隐窝进行成像。
Biomed Opt Express. 2017 Aug 17;8(9):4141-4151. doi: 10.1364/BOE.8.004141. eCollection 2017 Sep 1.
8
Twenty-five years of optical coherence tomography: the paradigm shift in sensitivity and speed provided by Fourier domain OCT [Invited].光学相干断层扫描的二十五年:傅里叶域光学相干断层扫描带来的灵敏度和速度的范式转变[特邀报告]
Biomed Opt Express. 2017 Jun 15;8(7):3248-3280. doi: 10.1364/BOE.8.003248. eCollection 2017 Jul 1.
9
Evaluating anesthetic protocols for functional blood flow imaging in the rat eye.评估大鼠眼部功能血流成像的麻醉方案。
J Biomed Opt. 2017 Jan 1;22(1):16005. doi: 10.1117/1.JBO.22.1.016005.
10
TOWARD QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Visualizing Blood Flow Speeds in Ocular Pathology Using Variable Interscan Time Analysis.迈向定量光学相干断层扫描血管造影术:使用可变扫描间期分析可视化眼部病理学中的血流速度
Retina. 2016 Dec;36 Suppl 1(Suppl 1):S118-S126. doi: 10.1097/IAE.0000000000001328.