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纳米技术在早期癌症检测中的应用。

Nanotechnology for early cancer detection.

机构信息

Department of Chemistry, National Core Research Center for Systems Bio-Dynamics, Pohang University of Science and Technology, Pohang 790-784, Korea.

出版信息

Sensors (Basel). 2010;10(1):428-55. doi: 10.3390/s100100428. Epub 2010 Jan 6.

Abstract

Vast numbers of studies and developments in the nanotechnology area have been conducted and many nanomaterials have been utilized to detect cancers at early stages. Nanomaterials have unique physical, optical and electrical properties that have proven to be very useful in sensing. Quantum dots, gold nanoparticles, magnetic nanoparticles, carbon nanotubes, gold nanowires and many other materials have been developed over the years, alongside the discovery of a wide range of biomarkers to lower the detection limit of cancer biomarkers. Proteins, antibody fragments, DNA fragments, and RNA fragments are the base of cancer biomarkers and have been used as targets in cancer detection and monitoring. It is highly anticipated that in the near future, we might be able to detect cancer at a very early stage, providing a much higher chance of treatment.

摘要

大量的研究和发展在纳米技术领域已经进行了,许多纳米材料已经被用于在早期阶段检测癌症。纳米材料具有独特的物理、光学和电学特性,在传感方面被证明非常有用。量子点、金纳米粒子、磁性纳米粒子、碳纳米管、金纳米线和许多其他材料已经开发出来,同时也发现了广泛的生物标志物来降低癌症生物标志物的检测限。蛋白质、抗体片段、DNA 片段和 RNA 片段是癌症生物标志物的基础,已被用作癌症检测和监测的靶点。人们高度期待,在不久的将来,我们可能能够在早期阶段检测到癌症,从而提供更高的治疗机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0721/3270850/4cf990b0931a/sensors-10-00428f1.jpg

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