Urkalan Kaveri Balan, Sigman Matthew S
Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, UT 84112, USA.
Angew Chem Int Ed Engl. 2009;48(17):3146-9. doi: 10.1002/anie.200900218.
A cationic palladium complex catalyzes the title transformations, which are thought to proceed via a pi-allyl or pi-benzyl intermediate. The regioselectivity of the reaction (1,2- or 1,1-difunctionalization) depends on the type of terminal double bond (conjugated or nonconjugated) in the substrate (see scheme) and appears to be controlled by the relative rates of beta-hydride elimination and transmetalation. DMA=dimethylacetamide, Tf=triflyl.
一种阳离子钯配合物催化标题所示的转化反应，该反应被认为是通过π-烯丙基或π-苄基中间体进行的。反应的区域选择性（1,2-或1,1-双官能化）取决于底物中末端双键的类型（共轭或非共轭）（见方案），并且似乎受β-氢消除和转金属化的相对速率控制。DMA = 二甲基乙酰胺，Tf = 三氟甲磺酰基。
