伯基特淋巴瘤和鼻咽癌中的平滑肌抗体。
Smooth muscle antibody in Burkitt's lymphoma and in nasopharyngeal carcinoma.
作者信息
Lamelin J P, Williams E H, Souissi T, De-Thé G, Gabbiani G
出版信息
Clin Exp Immunol. 1977 Apr;28(1):157-62.
Abstract
Smooth muscle antibodies (SMA) with specificity for actin, were found with a higher frequency in sera from Burkitt's lymphoma (BL) and nasopharyngeal carcinoma (NPC) patients than in sera from matched controls. No correlation could be found between SMA and anti-Epstein-Barr virus (EBV) antibody titres. There was no parallelism, in individual sera, between the finding of SMA and the occurrence of cold lymphocytotoxins, aother antibody activity found with an abnormally high frequency among BL and NPC patients. The reason why actin, a weak antigen in experimental animals, may become immunogenic in humans remains unexplained.
摘要
对肌动蛋白具有特异性的平滑肌抗体（SMA）在伯基特淋巴瘤（BL）和鼻咽癌（NPC）患者血清中的出现频率高于匹配对照组的血清。未发现SMA与抗爱泼斯坦-巴尔病毒（EBV）抗体滴度之间存在相关性。在个体血清中，SMA的检测结果与冷淋巴细胞毒素（在BL和NPC患者中异常高频率出现的另一种抗体活性）的出现之间没有平行关系。肌动蛋白在实验动物中是一种弱抗原，但在人类中可能具有免疫原性，其原因尚不清楚。
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本文引用的文献
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