针对爱泼斯坦-巴尔病毒决定抗原的抗体依赖性细胞毒性（ADCC）。III. 伯基特淋巴瘤患者血清中的反应性与肿瘤发展的关系。
Antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus-determined antigens. III. Reactivity in sera from patients with Burkitt's lymphoma in relation to tumour development.
作者信息
Jondal M, Gunven P
出版信息
Clin Exp Immunol. 1977 Jul;29(1):11-5.
Abstract
Sera from patients with Burkitt's lymphoma (BL) were tested for antibody-dependent cellular cytotoxicity (ADCC) against Epstein-Barr virus (EBV) determined antigens and for antibodies directed against various EBV-specific antigens. No correlation was found between EBV serology and ADCC in sera selected for high or low titres against the membrane antigens (MA) or in consecutive sera from three patients with isolated late tumour recurrences. Furthermore, no correlation was found between ADCC and tumour development.
摘要
对伯基特淋巴瘤（BL）患者的血清进行了检测，以确定其针对爱泼斯坦 - 巴尔病毒（EBV）抗原的抗体依赖性细胞毒性（ADCC），以及针对各种EBV特异性抗原的抗体。在针对膜抗原（MA）选择的高滴度或低滴度血清中，或在三名孤立的晚期肿瘤复发患者的连续血清中，未发现EBV血清学与ADCC之间存在相关性。此外，未发现ADCC与肿瘤发展之间存在相关性。
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