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高血压:关于风险与预后的思考

Hypertension: reflections on risks and prognostication.

作者信息

Kannel William B

机构信息

Boston University School of Medicine/Framingham Heart Study, Framingham, MA 01702-5827, USA.

出版信息

Med Clin North Am. 2009 May;93(3):541-58, Table of Contents. doi: 10.1016/j.mcna.2009.02.006.

DOI:10.1016/j.mcna.2009.02.006
PMID:19427490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3719976/
Abstract

Framingham Heart Study cardiovascular disease prospective population epidemiologic research has played an important role in the evolution of modern cohort study design and the advancement of preventive cardiology. To date no single essential factor has been identified; multiple interrelated factors are promoting increased risk for development of CHD. Elevated blood pressure has emerged as a prominent member of cardiovascular risk factors. The study's documentation of a strong link of blood pressure to development of cardiovascular events stimulated the pharmaceutical industry to develop medications for controlling blood pressure and, in turn, national campaigns to combat hypertension and its adverse vascular outlook.

摘要

弗明汉心脏研究心血管疾病前瞻性人群流行病学研究在现代队列研究设计的发展以及预防心脏病学的进步中发挥了重要作用。迄今为止,尚未确定单一的关键因素;多种相互关联的因素正在促使冠心病发生风险增加。血压升高已成为心血管危险因素中的一个突出因素。该研究记录了血压与心血管事件发生之间的紧密联系,这刺激了制药行业开发控制血压的药物,进而推动了全国范围内抗击高血压及其不良血管预后的运动。

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本文引用的文献

1
General cardiovascular risk profile for use in primary care: the Framingham Heart Study.用于初级保健的一般心血管风险概况:弗雷明汉心脏研究
Circulation. 2008 Feb 12;117(6):743-53. doi: 10.1161/CIRCULATIONAHA.107.699579. Epub 2008 Jan 22.
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Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.全国高血压防治联合委员会第七次报告:预防、检测、评估及治疗
Hypertension. 2003 Dec;42(6):1206-52. doi: 10.1161/01.HYP.0000107251.49515.c2. Epub 2003 Dec 1.
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Factors of risk in the development of coronary heart disease--six year follow-up experience. The Framingham Study.冠心病发病的危险因素——六年随访经验。弗明汉姆研究。
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