Kannel William B
Boston University School of Medicine/Framingham Heart Study, Framingham, MA 01702-5827, USA.
Med Clin North Am. 2009 May;93(3):541-58, Table of Contents. doi: 10.1016/j.mcna.2009.02.006.
Framingham Heart Study cardiovascular disease prospective population epidemiologic research has played an important role in the evolution of modern cohort study design and the advancement of preventive cardiology. To date no single essential factor has been identified; multiple interrelated factors are promoting increased risk for development of CHD. Elevated blood pressure has emerged as a prominent member of cardiovascular risk factors. The study's documentation of a strong link of blood pressure to development of cardiovascular events stimulated the pharmaceutical industry to develop medications for controlling blood pressure and, in turn, national campaigns to combat hypertension and its adverse vascular outlook.
弗明汉心脏研究心血管疾病前瞻性人群流行病学研究在现代队列研究设计的发展以及预防心脏病学的进步中发挥了重要作用。迄今为止,尚未确定单一的关键因素;多种相互关联的因素正在促使冠心病发生风险增加。血压升高已成为心血管危险因素中的一个突出因素。该研究记录了血压与心血管事件发生之间的紧密联系,这刺激了制药行业开发控制血压的药物,进而推动了全国范围内抗击高血压及其不良血管预后的运动。