• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

社区居住的中老年成年人非处方使用止痛药情况:全国药物使用和健康调查

Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.

作者信息

Blazer Dan G, Wu Li-Tzy

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Am Geriatr Soc. 2009 Jul;57(7):1252-7. doi: 10.1111/j.1532-5415.2009.02306.x. Epub 2009 May 21.

DOI:10.1111/j.1532-5415.2009.02306.x
PMID:19486199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2752277/
Abstract

OBJECTIVES

To estimate the frequency, distribution, and correlates of nonprescription use of pain relievers by middle-aged and elderly persons in the United States.

DESIGN

Cross-sectional data analysis of a national community survey.

SETTING

The 2005 and 2006 National Surveys on Drug Use and Health.

PARTICIPANTS

Ten thousand nine hundred fifty-three respondents aged 50 and older (6,717 aged 50-64 and 4,236 aged > or = 65).

MEASUREMENTS

Social and demographic variables, detailed assessment of nonprescription use (and abuse) of prescription pain relievers (e.g., acetaminophen with codeine, morphine), substance use, major depression, self-reported medical illnesses, and self-rated health.

RESULTS

A small proportion of the sample (1.4%) reported nonprescription use of prescription pain relievers during the previous year. Combinations of acetaminophen and hydrocodone or propoxyphene were the most commonly used drugs. Use was associated with younger age (odds ratio (OR)=2.39, 95% confidence interval (CI)=1.31-4.36), American Indian and Alaska native (OR=8.78, 95% CI=2.50-30.85), and use of marijuana (OR=7.07, 95% CI=3.99-12.53). Fewer than 10% of nonprescription users were abusing these medications or dependent upon them.

CONCLUSION

In a representative sample of middle-aged and older adults, nonprescription use of prescription pain relievers is relatively uncommon, but the much higher use by middle-aged adults suggests that, as this cohort ages, the problem may increase in elderly people.

摘要

目的

评估美国中年及老年人非处方使用止痛剂的频率、分布情况及其相关因素。

设计

对一项全国性社区调查进行横断面数据分析。

背景

2005年和2006年全国药物使用和健康调查。

参与者

10953名年龄在50岁及以上的受访者(6717名年龄在50 - 64岁之间,4236名年龄在65岁及以上)。

测量指标

社会和人口统计学变量、对处方止痛剂非处方使用(及滥用)的详细评估(如对乙酰氨基酚与可待因、吗啡)、物质使用情况、重度抑郁症、自我报告的疾病以及自我评估的健康状况。

结果

样本中一小部分人(1.4%)报告在前一年非处方使用了处方止痛剂。对乙酰氨基酚与氢可酮或丙氧芬的组合是最常用的药物。使用与较年轻的年龄(优势比(OR)=2.39,95%置信区间(CI)=1.31 - 4.36)、美国印第安人和阿拉斯加原住民(OR=8.78,95% CI=2.50 - 30.85)以及使用大麻(OR=7.07,95% CI=3.99 - 12.53)有关。非处方使用者中不到10%的人滥用这些药物或对其有依赖。

结论

在中年及老年人的代表性样本中,非处方使用处方止痛剂相对不常见,但中年成年人的使用比例高得多,这表明随着这一群体年龄增长,老年人中的这个问题可能会增加。

相似文献

1
Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.社区居住的中老年成年人非处方使用止痛药情况:全国药物使用和健康调查
J Am Geriatr Soc. 2009 Jul;57(7):1252-7. doi: 10.1111/j.1532-5415.2009.02306.x. Epub 2009 May 21.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Non-prescribed use of pain relievers among adolescents in the United States.美国青少年非处方使用止痛药物的情况。
Drug Alcohol Depend. 2008 Apr 1;94(1-3):1-11. doi: 10.1016/j.drugalcdep.2007.09.023. Epub 2007 Dec 3.
4
Correlates of Abusing and Misusing Over-the-Counter Pain Relievers Among Adult Population of Wrocław (Poland).波兰弗罗茨瓦夫成年人群中滥用和误用非处方止痛药的相关因素
Adv Clin Exp Med. 2016 Mar-Apr;25(2):349-60. doi: 10.17219/acem/58887.
5
Misuse and dependence on non-prescription codeine analgesics or sedative H1 antihistamines by adults: a cross-sectional investigation in France.成年人非处方可待因类镇痛药和镇静 H1 抗组胺药的滥用和依赖:法国的一项横断面调查。
PLoS One. 2013 Oct 3;8(10):e76499. doi: 10.1371/journal.pone.0076499. eCollection 2013.
6
Prevalence and drug use correlates of extra-medical use of prescription medications for sleep among adults in the United States: Results of the 2015-2018 National Survey on Drug Use and Health.美国成年人中处方药物非医疗用途使用的流行情况和药物使用相关因素:2015-2018 年全国药物使用与健康调查结果。
Pharmacol Biochem Behav. 2021 May;204:173169. doi: 10.1016/j.pbb.2021.173169. Epub 2021 Mar 6.
7
Prescription and nonprescription drug misuse and abuse in community pharmacies in Iraq: a cross-sectional survey.伊拉克社区药店中处方和非处方药物的误用和滥用:一项横断面调查。
Int J Pharm Pract. 2024 Nov 14;32(6):461-469. doi: 10.1093/ijpp/riae045.
8
Prescription and Nonprescription Sleep Product Use Among Older Adults in the United States.美国老年人的处方和非处方睡眠产品使用情况。
Am J Geriatr Psychiatry. 2019 Jan;27(1):32-41. doi: 10.1016/j.jagp.2018.09.004. Epub 2018 Sep 14.
9
Analgesic use among community-dwelling people aged 75 years and older: A population-based interview study.75岁及以上社区居民的镇痛药物使用情况:一项基于人群的访谈研究。
Am J Geriatr Pharmacother. 2010 Jun;8(3):233-44. doi: 10.1016/j.amjopharm.2010.05.001.
10
Misuse of Prescription Pain Relievers, Stimulants, Tranquilizers, and Sedatives Among U.S. Older Adults Aged ≥50 Years.美国≥50 岁的老年人中处方止痛药、兴奋剂、镇静剂和安定剂的滥用。
Am J Prev Med. 2020 Dec;59(6):860-872. doi: 10.1016/j.amepre.2020.04.028. Epub 2020 Nov 18.

引用本文的文献

1
Rising Trend of Substance Abuse Among Older Adults: A Review Focusing on Screening and Management.老年人药物滥用呈上升趋势:聚焦筛查与管理的综述
Cureus. 2024 Dec 31;16(12):e76659. doi: 10.7759/cureus.76659. eCollection 2024 Dec.
2
The association between cannabis use and subjective memory complaints in older adults in the United States.美国老年人中大麻使用与主观记忆主诉之间的关联。
J Int Neuropsychol Soc. 2023 Nov;29(9):870-877. doi: 10.1017/S1355617723000061. Epub 2023 Feb 20.
3
Impacts of medical and non-medical cannabis on the health of older adults: Findings from a scoping review of the literature.医用和非医用大麻对老年人健康的影响:文献综述的研究结果。
PLoS One. 2023 Feb 17;18(2):e0281826. doi: 10.1371/journal.pone.0281826. eCollection 2023.
4
Pattern and predictors of medication use among adults in southwestern Nigeria: A community-based cross-sectional study.尼日利亚西南部成年人用药模式和预测因素:一项基于社区的横断面研究。
Pharmacol Res Perspect. 2023 Feb;11(1):e01017. doi: 10.1002/prp2.1017.
5
Mental health care for older adults: recent advances and new directions in clinical practice and research.老年人的心理健康护理:临床实践与研究的最新进展及新方向
World Psychiatry. 2022 Oct;21(3):336-363. doi: 10.1002/wps.20996.
6
Opioid-involved prescription drug misuse and poly-prescription drug misuse in U.S. older adults.美国老年人群体中涉及阿片类药物的处方药物滥用和多处方药物滥用。
Aging Ment Health. 2021 Dec;25(12):2365-2373. doi: 10.1080/13607863.2020.1839859. Epub 2020 Nov 2.
7
The influence of undertreated chronic pain in a national survey: Prescription medication misuse among American indians, Asian Pacific Islanders, Blacks, Hispanics and whites.一项全国性调查中未得到充分治疗的慢性疼痛的影响:美国印第安人、亚太岛民、黑人、西班牙裔和白人中处方药的滥用情况。
SSM Popul Health. 2020 Mar 14;11:100563. doi: 10.1016/j.ssmph.2020.100563. eCollection 2020 Aug.
8
Association of Medicare Part D Benzodiazepine Coverage Expansion With Changes in Fall-Related Injuries and Overdoses Among Medicare Advantage Beneficiaries.医疗保险 D 部分苯二氮䓬类药物覆盖范围扩大与医疗保险优势受益人的跌倒相关伤害和过量用药变化的关联。
JAMA Netw Open. 2020 Apr 1;3(4):e202051. doi: 10.1001/jamanetworkopen.2020.2051.
9
Prescription Drug Misuse: Taking a Lifespan Perspective.处方药滥用:从生命周期角度审视
Subst Abuse. 2020 Mar 5;14:1178221820909352. doi: 10.1177/1178221820909352. eCollection 2020.
10
Auriculatone Sulfate Effectively Protects Mice Against Acetaminophen-Induced Liver Injury.硫酸 Auriculatone 能有效保护小鼠免受对乙酰氨基酚引起的肝损伤。
Molecules. 2019 Oct 9;24(20):3642. doi: 10.3390/molecules24203642.

本文引用的文献

1
Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.青少年中处方止痛药的滥用与依赖:一项全国代表性研究。
J Am Acad Child Adolesc Psychiatry. 2008 Sep;47(9):1020-9. doi: 10.1097/CHI.0b013e31817eed4d.
2
Epidemiology of chronic pain in Denmark: an update.丹麦慢性疼痛的流行病学:最新情况
Eur J Pain. 2009 Mar;13(3):287-92. doi: 10.1016/j.ejpain.2008.04.007. Epub 2008 Jun 10.
3
Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids.治疗性阿片类药物:关于阿片类药物使用增加、滥用及非医疗使用的复杂性和并发症的十年展望。
Pain Physician. 2008 Mar;11(2 Suppl):S63-88.
4
Prescription medication misuse and substance use disorder in VA primary care patients with chronic pain.退伍军人事务部慢性疼痛初级护理患者中的处方药滥用与物质使用障碍
Gen Hosp Psychiatry. 2008 Mar-Apr;30(2):93-9. doi: 10.1016/j.genhosppsych.2007.12.004.
5
Non-prescribed use of pain relievers among adolescents in the United States.美国青少年非处方使用止痛药物的情况。
Drug Alcohol Depend. 2008 Apr 1;94(1-3):1-11. doi: 10.1016/j.drugalcdep.2007.09.023. Epub 2007 Dec 3.
6
Gender and non-medical use of prescription opioids: results from a national US survey.性别与处方阿片类药物的非医疗用途:美国一项全国性调查的结果
Addiction. 2008 Feb;103(2):258-68. doi: 10.1111/j.1360-0443.2007.02056.x. Epub 2007 Nov 27.
7
Psychoactive drug abuse in older adults.老年人中的精神活性药物滥用
Am J Geriatr Pharmacother. 2006 Dec;4(4):380-94. doi: 10.1016/j.amjopharm.2006.10.002.
8
Opioid prescriptions soar: increase in legitimate use as well as abuse.阿片类药物处方量飙升:合法使用及滥用情况均有所增加。
JAMA. 2007 Jan 17;297(3):249-51. doi: 10.1001/jama.297.3.249.
9
Patterns of illicit drug use and opioid abuse in patients with chronic pain at initial evaluation: a prospective, observational study.慢性疼痛患者初次评估时的非法药物使用和阿片类药物滥用模式:一项前瞻性观察性研究。
Pain Physician. 2004 Oct;7(4):431-7.
10
Co-occurring DSM-IV drug abuse in DSM-IV drug dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions.《精神疾病诊断与统计手册》第四版(DSM-IV)中药物滥用与药物依赖并发情况:来自国家酒精及相关状况流行病学调查的结果
Drug Alcohol Depend. 2005 Oct 1;80(1):117-23. doi: 10.1016/j.drugalcdep.2005.03.010. Epub 2005 Apr 18.