意大利中部托斯卡纳病毒的年龄依赖性血清阳性率及其与临床特征的相关性。
Age-dependent seroprevalence of Toscana virus in central Italy and correlation with the clinical profile.
作者信息
Terrosi C, Olivieri R, Bianco C, Cellesi C, Cusi M G
机构信息
Department of Molecular Biology, Microbiology Section, University of Siena, Siena, Italy.
出版信息
Clin Vaccine Immunol. 2009 Aug;16(8):1251-2. doi: 10.1128/CVI.00376-08. Epub 2009 Jun 24.
Abstract
In order to estimate the antibody prevalence rates for Toscana virus (TOSV) among children and adults, we evaluated the seroprevalence of TOSV in a population (n = 2,737) living in Tuscany during the period of 1999 to 2006. The seroprevalence rate was 19.8% in adults and 5.8% in children, showing an age-dependent increase in TOSV-specific immunity. Meningitis due to TOSV infection was more frequent in adults than in children.
摘要
为了估计托斯卡纳病毒（TOSV）在儿童和成人中的抗体流行率，我们评估了1999年至2006年期间居住在托斯卡纳的人群（n = 2737）中TOSV的血清流行率。成人血清流行率为19.8%，儿童为5.8%，表明TOSV特异性免疫力随年龄增长而增加。由TOSV感染引起的脑膜炎在成人中比在儿童中更常见。
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