Tucker-Drob Elliot M, Harden K Paige, Turkheimer Eric
Department of Psychology, University of Virginia, P.O. Box 400400, Charlottesville, VA, 22904-4400, USA.
Behav Genet. 2009 Sep;39(5):461-71. doi: 10.1007/s10519-009-9288-6. Epub 2009 Jul 25.
It is well-established that genetic factors account for large proportions of individual differences in multiple cognitive abilities. It is also well-established that individual differences in performance on many different cognitive ability measures are strongly correlated. Recent empirical investigations, however, have suggested two interesting qualifications to these well-established findings: Genetic variance in cognitive abilities is higher in richer home environments (gene-by-environment interaction), and common variance in different cognitive abilities is lower at higher levels of overall ability (nonlinear factor structure). Although they have been investigated independently, these two phenomena may interact, because richer environments are routinely associated with higher ability levels. Using simulation we demonstrate how un-modeled nonlinear factor structure can obscure interpretation of gene-by-environment interaction. We then reanalyze data from the National Collaborative Perinatal Project, previously used by Turkheimer et al. (2003; Psychol Science), with a two-step method to model both phenomena.
众所周知,遗传因素在多种认知能力的个体差异中占很大比例。同样众所周知的是,在许多不同认知能力测量中的表现个体差异密切相关。然而,最近的实证研究对这些既定发现提出了两个有趣的限定条件:在更富裕的家庭环境中,认知能力的遗传方差更高(基因与环境相互作用),并且在总体能力较高水平时,不同认知能力的共同方差较低(非线性因素结构)。尽管这两种现象已被独立研究,但它们可能相互作用,因为更丰富的环境通常与更高的能力水平相关。通过模拟,我们展示了未建模的非线性因素结构如何掩盖基因与环境相互作用的解释。然后,我们用一种两步法对这两种现象进行建模,重新分析了国家围产期协作项目的数据,该数据此前由Turkheimer等人(2003年;《心理科学》)使用。