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股骨头坏死的患病率:韩国全国范围内的流行病学分析。

Prevalence of osteonecrosis of the femoral head: a nationwide epidemiologic analysis in Korea.

机构信息

Department of Orthopedic Surgery, Inha University Hospital, Joongku, Incheon, South Korea.

出版信息

J Arthroplasty. 2009 Dec;24(8):1178-83. doi: 10.1016/j.arth.2009.05.022. Epub 2009 Jul 28.

Abstract

This study was performed to estimate the prevalence of osteonecrosis of the femoral head in Korea. Using medical claims data from the Korean National Health Insurance Corporation, all individuals treated under a diagnosis of osteonecrosis of the femoral head were identified for each year from 2002 to 2006. Among them, the number of true cases was estimated using a randomly collected validation sample of 382 patients for which the actual diagnosis was investigated by authors. The estimated yearly prevalence per 100 000 population ranged from 20.53 (20.13 <or= 95% confidence interval <or= 20.94) in 2002 to 37.96 (37.42 <or= 95% confidence interval <or= 38.51) in 2006. The average estimated number of annual prevalent cases was 14 103, indicating 28.91 per 100 000 average prevalence over a 5-year period. Males predominated. We found that 32.4% had history of alcohol abuse, and 14.6% was related to steroid. Bilateral involvement was noticed in 37%. Besides arthroplasty, decompression was the most frequently performed joint-preserving procedure. We believe that the results serve as important baseline for understanding the disease.

摘要

本研究旨在估计韩国股骨头坏死的患病率。使用韩国国家健康保险公社的医疗索赔数据,从 2002 年到 2006 年,每年都对股骨头坏死的治疗患者进行了统计。其中,通过对随机抽取的 382 名患者的验证样本(实际诊断由作者进行调查),对实际病例数进行了估计。估计的每年每 10 万人的患病率从 2002 年的 20.53(20.13<95%置信区间<20.94)到 2006 年的 37.96(37.42<95%置信区间<38.51)。平均估计每年的发病例数为 14103 例,表明在 5 年期间的平均患病率为 28.91/10 万人。男性居多。我们发现 32.4%的患者有酗酒史,14.6%与皮质类固醇有关。三分之一的患者为双侧受累。除了关节置换术,减压是最常进行的关节保留手术。我们认为,这些结果为了解该疾病提供了重要的基线数据。

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