Kohnen Thomas, Klaproth Oliver K, Bühren Jens
Department of Ophthalmology, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, Frankfurt am Main, Germany.
Ophthalmology. 2009 Sep;116(9):1697-706. doi: 10.1016/j.ophtha.2009.03.052. Epub 2009 Jul 29.
To determine the effect of intraocular lens (IOL) asphericity on quality of vision after cataract removal.
Intraindividual, prospective, randomized clinical trial.
Twenty-six cataract patients received 2, one-piece, blue-light-filtering hydrophobic acrylic IOLs each.
One eye was implanted with a spherical (SN60AT, Alcon) and the contralateral eye with an aspheric (SN60WF, Alcon) IOL with -0.2 mum spherical aberration (SA). All trial-specific measurements (corneal topography, wavefront sensing, high-contrast visual acuity [HCVA], contrast sensitivity [CS]) were performed 6 months after surgery. A paired Student t-test or Wilcoxon test was used to check intergroup differences.
Absolute values and intraindividual differences (Delta(i)) of corneal and ocular higher order aberrations and best-corrected visual Strehl ratio based on the optical transfer function (BCVSOTF) values for virtual pupil diameters of 3, 4, 5, and 6 mm were computed. Photopic and mesopic HCVA, photopic, and high-mesopic CS as well as high-mesopic disability glare (DG) were measured using the Frankfurt-Freiburg Contrast and Acuity Test System.
No intergroup difference of demographic data, pupillometry, and corneal aberrations were observed. Coma and trefoil root mean square and SA were significantly lower in the aspheric group resulting in higher BCVSOTF, mesopic HCVA, and photopic and high mesopic CS. All Delta(i) values with exception of photopic HCVA and DG indicated significantly better performance of the aspheric IOL.
An aspheric IOL with -0.2 microm SA provide higher quality of vision than spherical IOL in terms of retinal image quality, mesopic HCVA and CS.
FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosures may be found after the references.
确定人工晶状体(IOL)非球面性对白内障摘除术后视觉质量的影响。
个体内、前瞻性、随机临床试验。
26例白内障患者,每例患者均植入2枚一体式蓝光滤过型疏水丙烯酸酯人工晶状体。
一只眼植入球面人工晶状体(SN60AT,爱尔康公司),对侧眼植入非球面人工晶状体(SN60WF,爱尔康公司),后者具有-0.2μm的球差(SA)。所有特定试验测量(角膜地形图、波前传感、高对比度视力[HCVA]、对比敏感度[CS])均在术后6个月进行。采用配对学生t检验或威尔科克森检验来检查组间差异。
计算3、4、5和6mm虚拟瞳孔直径下基于光学传递函数(BCVSOTF)值的角膜和眼高阶像差的绝对值及个体内差异(Delta(i)),以及最佳矫正视力斯特列尔比值。使用法兰克福-弗莱堡对比度和视力测试系统测量明视和中间视觉HCVA、明视和高中间视觉CS以及高中间视觉失能眩光(DG)。
未观察到组间在人口统计学数据、瞳孔测量和角膜像差方面的差异。非球面组的彗差、三叶草像差均方根和球差显著更低,从而导致更高的BCVSOTF、中间视觉HCVA以及明视和高中间视觉CS。除明视HCVA和DG外,所有Delta(i)值均表明非球面人工晶状体的性能显著更好。
就视网膜图像质量、中间视觉HCVA和CS而言,具有-0.2μm球差的非球面人工晶状体比球面人工晶状体提供更高的视觉质量。
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