Gellert A R, Gellert S L, Iliffe S R
St. Mary's Hospital Medical School, London.
Br J Gen Pract. 1990 May;40(334):197-201.
A study was set up to examine the prevalence and management of asthma symptoms in a London inner city general practice. All case records were examined and evidence of past or currently active asthma or wheezing illness was identified in 1032 out of 11,148 records (9.3%). This gave a cumulative prevalence of asthma or wheezing illness of 7.2% among adults and 19.5% among children aged 15 years or under. These figures are consistent with previous estimates of prevalence in the UK published since the mid 1960s. In 92.5% of cases in which information was available, the initial diagnosis of asthma or decision to prescribe a bronchodilator was made in primary care. Only nine cases (0.9%) had evidence of recurrent wheezing without the benefit of bronchodilator therapy at any time. There was significant delay in diagnosis in children under five years compared with older children or adults. There was a significant association between a formal diagnosis of 'asthma' in the case notes and the inclination of general practitioners to monitor peak expiratory flow or offer inhaled bronchodilator or corticosteroid therapy. Of 111 asthmatics (83 adults and 28 children aged five to 15 years) with previously 'severe' disease who sought medical advice for their asthma over a 12 month period, 91.6% of adults and 92.9% of children received bronchodilator therapy; nevertheless, only 47.0% of adults and 14.3% of children received inhaled corticosteroids and only 12.0% of adults and 28.0% of children received inhaled cromoglycate. Only 59.0% of adults and 46.4% of children had at least one measurement of peak expiratory flow during the 12 months.(ABSTRACT TRUNCATED AT 250 WORDS)
一项研究旨在调查伦敦市中心一家普通诊所中哮喘症状的患病率及管理情况。研究人员检查了所有病例记录,在11148份记录中,有1032份(9.3%)显示有过去或当前活动性哮喘或喘息疾病的证据。这使得哮喘或喘息疾病在成年人中的累积患病率为7.2%,在15岁及以下儿童中为19.5%。这些数字与自20世纪60年代中期以来英国公布的先前患病率估计一致。在92.5%有可用信息的病例中,哮喘的初步诊断或开具支气管扩张剂的决定是在初级保健中做出的。只有9例(0.9%)有反复喘息的证据,且在任何时候都未接受支气管扩张剂治疗。与大龄儿童或成年人相比,五岁以下儿童的诊断存在显著延迟。病例记录中正式诊断为“哮喘”与全科医生监测呼气峰值流速或提供吸入性支气管扩张剂或皮质类固醇治疗的倾向之间存在显著关联。在12个月内就哮喘寻求医疗建议的111名哮喘患者(83名成年人和28名5至15岁儿童)中,先前患有“严重”疾病,91.6%的成年人和92.9%的儿童接受了支气管扩张剂治疗;然而,只有47.0%的成年人和14.3%的儿童接受了吸入性皮质类固醇治疗,只有12.0%的成年人和28.0%的儿童接受了吸入性色甘酸钠治疗。在这12个月期间,只有59.0%的成年人和46.4%的儿童至少进行了一次呼气峰值流速测量。(摘要截选至250字)