苯并[d]恶唑-4,7-二酮的合成及抑菌活性
Synthesis and antifungal activity of benzo[d]oxazole-4,7-diones.
机构信息
College of Pharmacy, Ewha Womans University, Seodaemun-ku, Seoul 120-750, Republic of Korea.
出版信息
Bioorg Med Chem Lett. 2009 Oct 15;19(20):5924-6. doi: 10.1016/j.bmcl.2009.08.062. Epub 2009 Aug 21.
PMID:19733068
Abstract
Benzo[d]oxazole-4,7-diones were synthesized and tested for in vitro antifungal activity against fungi. Among them tested, many compounds showed good antifungal activity. The results suggest that benzo[d]oxazole-4,7-diones would be potent antifungal agents.
摘要
苯并[d]恶唑-4,7-二酮被合成并测试了其对真菌的体外抗真菌活性。在测试的化合物中，许多化合物表现出良好的抗真菌活性。结果表明，苯并[d]恶唑-4,7-二酮可能是有效的抗真菌药物。
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