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西班牙儿科人群的药物使用情况:相关因素和时间趋势,1993-2003 年。

Medication consumption in the Spanish paediatric population: related factors and time trend, 1993-2003.

机构信息

Unit of Preventive Medicine and Public Health, Rey Juan Carlos University, Alcorcón, Madrid, Spain.

出版信息

Br J Clin Pharmacol. 2009 Sep;68(3):455-61. doi: 10.1111/j.1365-2125.2009.03449.x.

Abstract

AIMS

To ascertain the prevalence of consumption of medications in the Spanish paediatric population and to identify the factors associated with such consumption.

METHODS

This was a descriptive, cross-sectional study covering the Spanish adult population, using data drawn from the 1993 and 2003 Spanish National Health Surveys (SNHS). The 1993 and 2003 SNHS include data on 5280 and 6463 children, respectively, age range 0-15 years. The independent variables were sociodemographic and health-related, and the dependent variable was medications use. Using logistic multivariate regression models, we analysed the temporal evolution of medication consumption between 1993 and 2003.

RESULTS

The 1993 SNHS data revealed that 36.81% of the paediatric population had consumed some type of medication, whereas in 2003 this figure had dropped to 34%. Over the decade of study, there was a significant decrease in use of medications for catarrh, influenza, throat (P < 0.05), and an increase in consumption of pain-relieving drugs and/or fever-lowering, antibiotics and anti-allergy remedies. Multivariate analysis highlighted the association between medication consumption, negative perception of the child's health [odds ratio (OR) 2.84, 95% confidence interval (CI) 2.16, 3.72 in 1993, and OR 3.54, 95% CI 2.74, 4.56 in 2003] and medical visits to the physician across the 2 years (OR 12.09, 95% CI 10.13, 14.42 in 1993, and OR 7.17, 95% CI 6.06, 8.47 in 2003).

CONCLUSIONS

Although there was a significant decline in overall drug consumption in the Spanish paediatric population from 1993 to 2003, the prevalence of consumption of certain groups, such as analgesics, antipyretics and antibiotics, has risen.

摘要

目的

确定西班牙儿科人群中药物使用的流行情况,并确定与药物使用相关的因素。

方法

这是一项描述性、横断面研究,涵盖了西班牙成年人,使用了 1993 年和 2003 年西班牙国家健康调查(SNHS)的数据。1993 年和 2003 年 SNHS 分别包含了年龄在 0-15 岁的 5280 名和 6463 名儿童的数据。自变量为社会人口统计学和与健康相关的因素,因变量为药物使用情况。我们使用逻辑多元回归模型分析了 1993 年至 2003 年间药物使用的时间演变。

结果

1993 年 SNHS 数据显示,36.81%的儿科人群使用过某种类型的药物,而 2003 年这一比例降至 34%。在研究的十年中,用于治疗感冒、流感、喉咙痛的药物使用显著减少(P<0.05),而用于止痛、退烧、抗生素和抗过敏药物的使用则有所增加。多变量分析突出了药物使用与儿童健康的负面认知之间的关联[1993 年的比值比(OR)为 2.84,95%置信区间(CI)为 2.16-3.72,2003 年的 OR 为 3.54,95%CI 为 2.74-4.56],以及两年内看医生的就诊次数(1993 年的 OR 为 12.09,95%CI 为 10.13-14.42,2003 年的 OR 为 7.17,95%CI 为 6.06-8.47)。

结论

尽管 1993 年至 2003 年间西班牙儿科人群的总体药物使用量显著下降,但某些药物的使用(如止痛药、退烧药和抗生素)的流行率有所上升。

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