Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
Langmuir. 2010 Mar 2;26(5):3685-9. doi: 10.1021/la903162v.
Nanodiamonds (NDs) have versatile applications in electro-optical devices, sensors, and biomedicine. Owing to the difficulty in activation of the inert sp(3) C-H bonds on the surface of NDs, it is not trivial to modify the surface functionalities on NDs. A few functionalization methods have been reported in the literature for surface modification of NDs. Many of them, however, are either multiple steps/time-consuming, or require the use of highly toxic/environmentally unfriendly reagents, such as fluorine gas and sulfuric acid. It is necessary to develop a simple process for surface functionalization of NDs to have both hydrophobic and hydrophilic functional groups. In this report, a facile process was developed to allow easy and rapid surface modification of NDs to become dispersible in either water or organic solvents using the same process. The process involves surface graphitization of NDs, followed by radical initiated surface grafting of oligomers with various functionalities, including -C(=O)OCH(3), -COOH, -NH(2), or aliphatic moieties.
纳米金刚石（NDs）在光电设备、传感器和生物医学中有多种应用。由于 NDs 表面惰性的 sp(3) C-H 键难以激活，因此对 NDs 表面功能进行修饰并非易事。文献中已经报道了几种用于 NDs 表面修饰的功能化方法。然而，其中许多方法要么步骤繁琐/耗时较长，要么需要使用剧毒/对环境不友好的试剂，如氟气和硫酸。因此，有必要开发一种简单的 NDs 表面功能化方法，使其同时具有疏水性和亲水性官能团。在本报告中，开发了一种简便的方法，可使用相同的方法轻松快速地对 NDs 进行表面修饰，使其在水或有机溶剂中均具有良好的分散性。该方法涉及 NDs 的表面石墨化，然后通过自由基引发表面接枝具有各种官能团的低聚物，包括 -C(=O)OCH(3)、-COOH、-NH(2)或脂肪族基团。
