从马占相思果实中分离得到结构多样的马钱素。

Structurally diverse limonoids from the fruits of Swietenia mahagoni.

机构信息

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.

出版信息

J Nat Prod. 2009 Dec;72(12):2084-90. doi: 10.1021/np900522h.

DOI:10.1021/np900522h

PMID:19902967

Abstract

Eleven new mexicanolide-type limonoids, swietmanins A-I (1-4, 7-11), 2-hydroxy-3-O-isobutyrylproceranolide (5), 2-hydroxy-3-O-benzoylproceranolide (6), and a new andirobin-type limonoid, swietmanin J (12), together with 19 known compounds were isolated from the fruits of Swietenia mahagoni. Their structures were established on the basis of spectroscopic methods. These compounds were evaluated against a small panel of microorganisms.

摘要

从桃花心木的果实中分离得到了 11 个新的墨西哥内酯型 limonoids，分别为 swietmanins A-I（1-4、7-11）、2-羟基-3-O-异丁酰基普罗塞诺内酯（5）、2-羟基-3-O-苯甲酰基普罗塞诺内酯（6）和一个新的 andirobin 型 limonoid，swietmanin J（12），以及 19 个已知化合物。这些化合物的结构是基于光谱方法确定的。这些化合物对一组小型微生物进行了评估。