龙舌兰叶中的甾体皂苷。

Steroidal saponins from the leaves of Agave macroacantha.

机构信息

Institut de Chimie moléculaire de Reims (ICMR), UMR-CNRS 6229, Reims, France.

出版信息

Fitoterapia. 2010 Jul;81(5):371-4. doi: 10.1016/j.fitote.2009.11.002. Epub 2009 Nov 10.

DOI:10.1016/j.fitote.2009.11.002

PMID:19909800

Abstract

A new monodesmosidic spirostanol saponin, along with three known saponins was isolated from Agave macroacantha Zucc leaves. The structure of the new saponin was established as hecogenin-3-O-alpha-L-rhamnopyranosyl (1-->4) beta-D-xylopyranosyl (1-->3)[beta-D-glucopyranosyl (1-->2)] beta-D-glucopyranosyl (1-->4) beta-D-galactopyranoside. The (1)H and (13)C resonances of the four compounds were assigned using a combination of 1D and 2D NMR techniques including (1)H, (13)C, COSY, TOCSY, ROESY, HSQC and HMBC NMR and confirmed by mass spectrometry.

摘要

从龙舌兰 macroacantha Zucc 叶中分离得到一种新的单糖苷螺甾烷醇皂苷，以及三种已知的皂苷。新皂苷的结构被确定为海柯苷元-3-O-α-L-鼠李吡喃糖苷基（1-->4）β-D-木吡喃糖苷基（1-->3）[β-D-吡喃葡萄糖基（1-->2）]β-D-吡喃葡萄糖基（1-->4）β-D-吡喃半乳糖苷。使用 1D 和 2D NMR 技术（包括 1H、13C、COSY、TOCSY、ROESY、HSQC 和 HMBC NMR）组合，以及质谱，对这四种化合物的（1）H 和（13）C 共振进行了分配，并通过质谱进行了确认。