Geuze H J, Morré D J
Department of Cell Biology, Medical School, University of Utrecht, The Netherlands.
J Electron Microsc Tech. 1991 Jan;17(1):24-34. doi: 10.1002/jemt.1060170105.
The trans-Golgi apparatus reticulum is that portion of the Golgi apparatus located in the trans-most aspect of the stack exhibiting certain characteristic morphological and functional characteristics. The membranes of the trans-Golgi reticulum are reticular in form, thickened with plasma membrane-like characteristics and with a considerable portion of their surface covered by clathrin coats. The enzymes thiamine pyrophosphatase and sialyl- and galactosyl transferases are functional markers. Correlative studies show the trans-Golgi apparatus reticulum to be involved in glycoprotein, enzyme and receptor processing and sorting along multiple pathways. Sorting and transfer of constituents to lysosomes, to secretory granules, or to the plasma membrane emerge as dominant functions.
反式高尔基体网状结构是高尔基体位于堆叠最外侧的部分，呈现出某些特定的形态和功能特征。反式高尔基体网状结构的膜呈网状，具有类似质膜的增厚特征，其表面相当一部分被网格蛋白包被覆盖。硫胺素焦磷酸酶以及唾液酸和半乳糖基转移酶是其功能标记物。相关研究表明，反式高尔基体网状结构参与糖蛋白、酶和受体沿多种途径的加工和分选。将成分分选并转移至溶酶体、分泌颗粒或质膜成为其主要功能。
