Department of Psychology, University of York, Heslington, York YO10 5DD, UK.
Arch Dis Child. 2010 Feb;95(2):107-12. doi: 10.1136/adc.2009.160325. Epub 2009 Nov 29.
Cochlear implantation in one ear (unilateral implantation) has been the standard treatment for severe-profound childhood deafness. We assessed whether cochlear implantation in both ears (bilateral implantation) is associated with better listening skills, higher health-related quality of life (health utility) and higher general quality of life (QOL) than unilateral implantation.
Cross-sectional observational study.
University of York.
Fifty severely-profoundly deaf and 56 normally-hearing children recruited via a charity, the UK National Health Service and schools.
Thirty of the deaf children had received bilateral cochlear implants; 20 had unilateral cochlear implants.
Performance measures of children's listening skills; parental-proxy valuations of the deaf children's health utility obtained with the Health Utilities Index Mark 3 and of their QOL obtained with a visual analogue scale.
On average, bilaterally-implanted children performed significantly better than unilaterally implanted children on tests of sound localisation and speech perception in noise. After conservative imputation of missing data and while controlling for confounds, bilateral implantation was associated with increases of 18.5% in accuracy of sound localisation (95% CI 5.9 to 31.1) and of 3.7 dB in speech perception in noise (95% CI 0.9 to 6.5). Bilaterally-implanted children did not perform as well as normally-hearing children, on average. Bilaterally- and unilaterally-implanted children did not differ significantly in parental ratings of health utility (difference in medians 0.05, p>0.05) or QOL (difference in medians 0.01, p>0.05).
Compared with unilateral cochlear implantation, bilateral implantation is associated with better listening skills in severely-profoundly deaf children.
单耳植入（单侧植入）已成为重度-极重度儿童耳聋的标准治疗方法。我们评估双耳植入（双侧植入）是否比单侧植入更能提高听力技能、更高的健康相关生活质量（健康效用）和更高的总体生活质量（QOL）。
横断面观察性研究。
约克大学。
通过慈善机构、英国国民保健服务和学校招募的 50 名重度极重度聋儿和 56 名正常听力儿童。
30 名聋儿接受了双侧人工耳蜗植入；20 名聋儿接受了单侧人工耳蜗植入。
儿童听力技能表现测试；使用健康效用指数标记 3 进行父母代理评估的聋儿健康效用和使用视觉模拟量表进行的 QOL。
平均而言，双侧植入儿童在声音定位和噪声中言语感知测试中的表现明显优于单侧植入儿童。在对缺失数据进行保守插补并控制混杂因素后，双侧植入与声音定位准确性提高 18.5%（95%CI5.9 至 31.1）和噪声中言语感知提高 3.7dB（95%CI0.9 至 6.5）相关。双侧植入儿童的表现平均不如正常听力儿童。双侧植入和单侧植入儿童在父母对健康效用的评分（中位数差异 0.05，p>0.05）或 QOL（中位数差异 0.01，p>0.05）方面无显著差异。
与单侧人工耳蜗植入相比，双侧植入与重度极重度聋儿更好的听力技能相关。
