Neuropsychiatry Service, Hunter New England Mental Health, PO Box 833, Newcastle, NSW 2300, Australia.
J Neurol Neurosurg Psychiatry. 2010 Jun;81(6):602-7. doi: 10.1136/jnnp.2009.188003. Epub 2009 Dec 3.
To describe and characterise the Audio Recorded Cognitive Screen (ARCS), a novel instrument that uses an audio device to administer selected neuropsychological tests to unsupervised individuals who write their responses in a special booklet for later scoring.
The ARCS was administered to 733 individuals, comprising 550 from a normative community sample (mean age=59.14, range 18-84 years), 101 clinic patients and a separate validation sample of 82 community controls, who, together with the patients, underwent detailed neuropsychological assessments. These data were examined for the influence of demographic variables on ARCS performance, to establish normal performance and develop scoring routines, and to characterise the structure, reliability and validity of the instrument.
Age, gender and education influenced ARCS performance. ARCS tests were generally reliable and correlated well with corresponding conventional neuropsychological tests. Factor analyses indicated that the ARCS measures executive functioning/attention, memory, language, verbal fluency and visuospatial functioning. The ARCS discriminated well between normal (n=82), impaired (n=33) and demented (n=25) individuals, and significantly better than did the Mini Mental State Examination (MMSE), including on a single, demographically adjusted, global QuickARCS score obtainable in about 3 min of the clinician's time. Receiver Operating Characteristic analyses confirmed the superiority of the ARCS over MMSE as a screen for mild dementia (AUC 0.98, 99% CI 0.95 to 1.00) or cognitive impairment (AUC 0.90, 99% CI 0.83 to 0.97).
The ARCS has good validity and reliability, has a sound normative base and measures functioning in multiple cognitive domains while imposing minimal time demands upon the clinician.
描述和描述音频记录认知筛查(ARCS),这是一种新颖的工具,它使用音频设备为无人监督的个体提供选择的神经心理学测试,这些个体在特殊小册子中书写他们的答案,以便以后评分。
ARCS 对 733 名个体进行了测试,其中包括 550 名来自规范社区样本(平均年龄=59.14 岁,年龄范围 18-84 岁),101 名诊所患者和 82 名独立的社区对照组,他们与患者一起接受了详细的神经心理学评估。检查了这些数据对 ARCS 表现的影响,以确定正常表现并制定评分程序,并描述仪器的结构、可靠性和有效性。
年龄、性别和教育程度影响 ARCS 的表现。ARCS 测试通常是可靠的,与相应的常规神经心理学测试相关性良好。因子分析表明,ARCS 测量执行功能/注意力、记忆、语言、词汇流畅性和视空间功能。ARCS 能够很好地区分正常(n=82)、受损(n=33)和痴呆(n=25)个体,并且明显优于简易精神状态检查(MMSE),包括在大约 3 分钟的临床医生时间内获得的单一、人口统计学调整的快速 ARCS 总评分。受试者工作特征分析证实 ARCS 优于 MMSE 作为轻度痴呆(AUC 0.98,99%CI 0.95 至 1.00)或认知障碍(AUC 0.90,99%CI 0.83 至 0.97)的筛查。
ARCS 具有良好的有效性和可靠性,具有可靠的基准,可测量多个认知领域的功能,同时对临床医生的时间要求最小。