Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
J Nutr. 2010 Feb;140(2):411-4. doi: 10.3945/jn.109.114504. Epub 2009 Dec 23.
This article reviews key findings about the long-term impact of a nutrition intervention carried out by the Institute of Nutrition of Central America and Panama from 1969 to 1977. Results from follow-up studies in 1988-89 and 2002-04 show substantial impact on adult human capital and economic productivity. The 1988-89 study showed that adult body size and work capacity increased for those provided improved nutrition through age 3 y, whereas the 2002-04 follow-up showed that schooling was increased for women and reading comprehension and intelligence increased in both men and women. Participants were 26-42 y of age at the time of the 2002-04 follow-up, facilitating the assessment of economic productivity. Wages of men increased by 46% in those provided with improved nutrition through age 2 y. Findings for cardiovascular disease risk factors were heterogeneous; however, they suggest that improved nutrition in early life is unlikely to increase cardiovascular disease risk later in life and may indeed lower risk. In conclusion, the substantial improvement in adult human capital and economic productivity resulting from the nutrition intervention provides a powerful argument for promoting improvements in nutrition in pregnant women and young children.
这篇文章回顾了中美洲和巴拿马营养研究所 1969 年至 1977 年进行的营养干预的长期影响的关键发现。1988-89 年和 2002-04 年的后续研究结果表明,该干预对成年人的人力资本和经济生产力有实质性影响。1988-89 年的研究表明,通过 3 岁时提供改善的营养,成年人的身体大小和工作能力增加,而 2002-04 年的后续研究表明,女性的受教育程度增加,男性和女性的阅读理解和智力都有所提高。在 2002-04 年的后续研究中,参与者的年龄为 26-42 岁,这有利于评估经济生产力。在 2 岁时通过改善营养获得营养的男性的工资增加了 46%。心血管疾病风险因素的研究结果存在异质性;然而,它们表明,在生命早期改善营养不太可能增加晚年患心血管疾病的风险,实际上可能降低风险。总之,营养干预措施对成年人人力资本和经济生产力的显著改善为促进孕妇和幼儿营养改善提供了有力论据。