Spine Section, Department of Orthopaedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
Eur Spine J. 2010 May;19(5):691-8. doi: 10.1007/s00586-009-1266-4. Epub 2010 Jan 6.
We evaluated the clinical results of posterior decompression with instrumented fusion (PDF) for thoracic myelopathy due to ossification of the posterior longitudinal ligament (OPLL). A total of 24 patients underwent PDF, and their surgical outcomes were evaluated by the Japanese Orthopaedic Association (JOA) scores (0-11 points) and by recovery rates calculated at 3, 6, 9 and 12 months after surgery and at a mean final follow-up of 4 years and 5 months. The mean JOA score before surgery was 3.7 points. Although transient paralysis occurred immediately after surgery in one patient (3.8%), all patients showed neurological recovery at the final follow-up with a mean JOA score of 8.0 points and a mean recovery rate of 58.1%. The mean recovery rate at 3, 6, 9 and 12 months after surgery was 36.7, 48.8, 54.0 and 56.8%, respectively. The median time point that the JOA score reached its peak value was 9 months after surgery. No patient chose additional anterior decompression surgery via thoracotomy. The present findings demonstrate that despite persistent anterior impingement of the spinal cord by residual OPLL, PDF can result in considerable neurological recovery with a low risk of postoperative paralysis. Since neurological recovery progresses slowly after PDF, we suggest that additional anterior decompression surgery is not desirable during the early stage of recovery.
我们评估了后路减压联合内固定融合术(PDF)治疗后纵韧带骨化(OPLL)所致胸段脊髓病的临床效果。共 24 例患者接受了 PDF 治疗,通过日本矫形协会(JOA)评分(0-11 分)和术后 3、6、9 和 12 个月以及平均 4 年 5 个月的最终随访时的恢复率来评估手术结果。手术前平均 JOA 评分为 3.7 分。虽然有 1 例患者(3.8%)在手术后即刻出现一过性瘫痪,但所有患者在最终随访时均出现神经功能恢复,平均 JOA 评分为 8.0 分,平均恢复率为 58.1%。术后 3、6、9 和 12 个月的平均恢复率分别为 36.7%、48.8%、54.0%和 56.8%。JOA 评分达到峰值的中位时间点为术后 9 个月。没有患者选择通过开胸行前路减压手术。本研究结果表明,尽管残留的 OPLL 持续对脊髓前缘造成压迫,PDF 仍可导致显著的神经功能恢复,且术后瘫痪的风险较低。由于 PDF 后神经功能恢复较为缓慢,我们建议在恢复早期不进行额外的前路减压手术。