Huang Chang-Bing, Lu Zhong-Lin, Zhou Yifeng
Laboratory of Brain Processes (LOBES), Department of Psychology, University of Southern California, Los Angeles, CA, USA.
J Vis. 2009 Oct 27;9(11):24.1-14. doi: 10.1167/9.11.24.
What underlies contrast sensitivity improvements in adults with anisometropic amblyopia following perceptual learning in grating contrast detection? In this paper, we adopted the external noise approach (Z.-L. Lu & B. A. Dosher, 1998) to identify the mechanisms underlying perceptual learning in adults with anisometropic amblyopia. By measuring contrast thresholds in a range of external noise conditions at two performance levels (79.3% and 70.7%), we found that a mixture of internal additive noise reduction and external noise exclusion underlay training induced contrast sensitivity improvements in adults with anisometropic amblyopia. In comparison, normal adults exhibited only small amount of external noise exclusion under the same training conditions. The results suggest that neural plasticity may be more robust in amblyopia, lending further support of perceptual learning as a potential treatment for adult amblyopia.
在光栅对比度检测中，屈光参差性弱视成人通过知觉学习后对比度敏感性提高的潜在原因是什么？在本文中，我们采用外部噪声方法（Lu & Dosher，1998年）来确定屈光参差性弱视成人知觉学习的潜在机制。通过在两个表现水平（79.3%和70.7%）下测量一系列外部噪声条件下的对比度阈值，我们发现内部加性噪声降低和外部噪声排除的混合作用是屈光参差性弱视成人训练诱导对比度敏感性提高的基础。相比之下，正常成人在相同训练条件下仅表现出少量的外部噪声排除。结果表明，弱视患者的神经可塑性可能更强，这进一步支持了知觉学习作为成人弱视潜在治疗方法的观点。
