King's College London, UK.
Obes Facts. 2009;2(2):117-25. doi: 10.1159/000208517. Epub 2009 Apr 9.
This review discusses the physiology of the hormones leptin, adiponectin, resistin, peptide YY, and ghrelin and how each of these contributes to energy homoeostasis, weight regulation, and the pathogenesis of obesity. The relationship these hormones have with insulin and insulin resistance is also discussed, and the potential therapeutic use of each of these hormones is also considered.
这篇综述讨论了激素瘦素、脂联素、抵抗素、肽 YY 和生长激素释放肽的生理学,以及它们如何共同作用于能量稳态、体重调节和肥胖的发病机制。还讨论了这些激素与胰岛素和胰岛素抵抗的关系,以及它们各自的潜在治疗用途。