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在波兰分离出的德尔兹西氏病毒株的遗传变异

Genetic variance of Derzsy's disease strains isolated in Poland.

作者信息

Woźniakowski Grzegorz, Kozdruń Wojciech, Samorek-Salamonowicz Elzbieta

机构信息

Department of Poultry Viral Diseases, National Veterinary Research Institute, Al Partyzantów 57, 24-100 Puławy, Poland.

出版信息

J Mol Genet Med. 2009 Nov 30;3(2):210-6. doi: 10.4172/1747-0862.1000037.

Abstract

The aim of this study was the assessment of the genetic variance of Derzy's disease (GPV) strains isolated from cases occurring in Poland. The nucleotide and predicted aminoacid sequences of VP2 and VP3 surface proteins of the Polish GPV strains were compared with other strains previously isolated in Hungary, France, Germany, China and Taiwan. The observed genetic variance of the aminoacid sequence within the group of Polish strains was low and reached 5% of the overall analysed sequence. Considerable differences in aminoacid sequence were found in the case of Polish field GPV strains and Muscovy duck parvovirus strain MDPV FM which was also analysed in this study. The conducted investigations confirmed the presupposition that Polish GPV strains and strains previously isolated in Hungary and France share a common origin.

摘要

本研究的目的是评估从波兰发生的病例中分离出的德尔齐氏病(鹅细小病毒,GPV)毒株的遗传变异情况。将波兰GPV毒株的VP2和VP3表面蛋白的核苷酸序列及预测的氨基酸序列与先前在匈牙利、法国、德国、中国和台湾分离出的其他毒株进行了比较。在波兰毒株组内观察到的氨基酸序列遗传变异较低,占整个分析序列的5%。在本研究中还分析了波兰野地GPV毒株和番鸭细小病毒毒株MDPV FM,发现它们在氨基酸序列上存在显著差异。所进行的调查证实了波兰GPV毒株与先前在匈牙利和法国分离出的毒株具有共同起源这一假设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a50/2805842/57bb35f5df22/jmgm-03-210-g001.jpg

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