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1

Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines.从异硫氰酸铵、酰氯和芳肼合成功能化的 1,2,4-三唑-3-硫酮。

Mol Divers. 2010 Nov;14(4):763-6. doi: 10.1007/s11030-009-9218-9. Epub 2010 Jan 16.

2

FeCl3 promoted highly regioselective [3 + 2] cycloaddition of dimethyl 2-vinyl and aryl cyclopropane-1,1-dicarboxylates with aryl isothiocyanates.三氯化铁促进了二甲基 2-乙烯基和芳基环丙烷-1,1-二羧酸酯与芳基异硫氰酸酯的高区域选择性 [3 + 2] 环加成反应。

Org Biomol Chem. 2012 Jul 14;10(26):5032-5. doi: 10.1039/c2ob25682g. Epub 2012 May 31.

3

A one-pot synthesis of functionalized thiazoles from acid chlorides, secondary amines, ethyl bromopyruvate, and ammonium thiocyanate.由酰氯、仲胺、溴丙酮酸乙酯和硫氰酸铵一锅法合成功能化噻唑。

Mol Divers. 2009 Aug;13(3):295-300. doi: 10.1007/s11030-009-9114-3. Epub 2009 Feb 10.

4

Synthesis of New Planar-Chiral Linked [2.2]Paracyclophanes--([2.2]-Paracyclophanylcarbamoyl)-4-([2.2]Paracyclophanylcarboxamide, [2.2]Paracyclophanyl-Substituted Triazolthiones and -Substituted Oxadiazoles.新型平面手性联[2.2]对环芳烷的合成--([2.2]-对环芳基碳酰胺基)-4-([2.2]对环芳基甲酰胺基)、[2.2]对环芳基取代三唑硫酮和-取代恶二唑。

Molecules. 2020 Jul 22;25(15):3315. doi: 10.3390/molecules25153315.

5

Solvent-free synthesis of functionalized thiazoles using multicomponent reaction of isothiocyanates.利用异硫氰酸酯的多组分反应进行功能化噻唑的无溶剂合成。

Comb Chem High Throughput Screen. 2013 Nov;16(9):758-61. doi: 10.2174/13862073113169990036.

6

Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones.4-取代-3-(噻吩-2-基甲基)-Δ2-1,2,4-三唑啉-5-硫酮的合成及其潜在抗真菌活性

Acta Pharm. 2004 Sep;54(3):251-60.

7

Synthesis and biological activities of some novel aminomethyl derivatives of 4-substituted-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones.合成及一些新型氨基甲基衍生物的生物活性 4-取代-5-(2-噻吩基)-2,4-二氢-3H-1,2,4-三唑-3-硫酮。

Eur J Med Chem. 2013 May;63:340-6. doi: 10.1016/j.ejmech.2013.02.025. Epub 2013 Mar 1.

8

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.由5-[(4-氨基苯氧基)甲基]-4-烷基/芳基-2,4-二氢-3H-1,2,4-三唑-3-硫酮合成的一些新型硫脲衍生物的制备及其作为抗病毒/抗HIV和抗结核药物的评价

Eur J Med Chem. 2008 Feb;43(2):381-92. doi: 10.1016/j.ejmech.2007.04.010. Epub 2007 May 13.

9

1-Alkyl-3-amino-5-aryl-1H-[1,2,4]triazoles: novel synthesis via cyclization of N-acyl-S-methylisothioureas with alkylhydrazines and their potent corticotropin-releasing factor-1 (CRF(1)) receptor antagonist activities.1-烷基-3-氨基-5-芳基-1H-[1,2,4]三唑：通过N-酰基-S-甲基异硫脲与烷基肼环化反应的新合成方法及其强效促肾上腺皮质激素释放因子-1（CRF(1)）受体拮抗活性。

Bioorg Med Chem Lett. 2001 Dec 17;11(24):3165-8. doi: 10.1016/s0960-894x(01)00657-6.

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Acyl-isothiocyanates as efficient thiocyanate transfer reagents.酰基异硫氰酸酯作为高效的硫氰酸酯转移试剂。

Org Lett. 2009 Aug 6;11(15):3382-5. doi: 10.1021/ol901561j.

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从异硫氰酸铵、酰氯和芳肼合成功能化的 1,2,4-三唑-3-硫酮。

Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines.

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