Guiot H F, Peetermans W E, Sebens F W
Department of Infectious Diseases, University Hospital, Leiden, The Netherlands.
Eur J Clin Microbiol Infect Dis. 1991 Jan;10(1):32-4. doi: 10.1007/BF01967094.
After the occurrence of septicaemia with a vancomycin-resistant Enterococcus faecalis strain in a patient, it was decided to determine the number of carriers of vancomycin-resistant cocci among haematologic patients. During a period of six months 135 stool samples from 25 children, and 400 samples from 70 adults were studied. All samples from the children were negative for vancomycin-resistant cocci. Nine of the adult patients had cultures positive for cocci, all identified as enterococci, which were highly resistant to vancomycin (MIC greater than 250 micrograms/ml), sensitive to amoxicillin, moderately resistant to gentamicin, slightly resistant to teicoplanin, and sensitive to daptomycin. None of these patients had been given vancomycin prior to the isolation of the vancomycin-resistant enterococci.
一名患者发生了由耐万古霉素粪肠球菌菌株引起的败血症后，决定测定血液学患者中耐万古霉素球菌携带者的数量。在六个月的时间里，研究了来自25名儿童的135份粪便样本和来自70名成人的400份样本。所有儿童样本中耐万古霉素球菌均为阴性。9名成年患者的球菌培养呈阳性，均鉴定为肠球菌，对万古霉素高度耐药（最低抑菌浓度大于250微克/毫升），对阿莫西林敏感，对庆大霉素中度耐药，对替考拉宁轻度耐药，对达托霉素敏感。在分离出耐万古霉素肠球菌之前，这些患者均未使用过万古霉素。
