苯并四咪唑催化的氮丙啶酮的动态动力学拆分。
Benzotetramisole-catalyzed dynamic kinetic resolution of azlactones.
机构信息
Department of Chemistry, Washington University, Campus Box 1134, One Brookings Drive, St. Louis, Missouri 63130, USA.
出版信息
Org Lett. 2010 Feb 19;12(4):892-5. doi: 10.1021/ol902969j.
Abstract
Enantioselective acyl transfer catalyst benzotetramisole (BTM) has been found to promote dynamic kinetic resolution of azlactones providing di(1-naphthyl)methyl esters of alpha-amino acids with up to 96% ee.
摘要
手性酰基转移催化剂苯并四咪唑 (BTM) 已被发现可促进氮杂环丙烷酮的动态动力学拆分，得到的α-氨基酸的二(1-萘基)甲酯对映体过量值高达 96%。
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