Department of Otolaryngology-HNS, Stanford University, Stanford, CA 94305, USA. dhoonlee.biz+
Hear Res. 2010 May;263(1-2):198-203. doi: 10.1016/j.heares.2010.01.007. Epub 2010 Jan 25.
Middle-ear anatomy is integrally linked to both its normal function and its response to disease processes. Micro-CT imaging provides an opportunity to capture high-resolution anatomical data in a relatively quick and non-destructive manner. However, to optimally extract functionally relevant details, an intuitive means of reconstructing and interacting with these data is needed.
A micro-CT scanner was used to obtain high-resolution scans of freshly explanted human temporal bones. An advanced volume renderer was adapted to enable real-time reconstruction, display, and manipulation of these volumetric datasets. A custom-designed user interface provided for semi-automated threshold segmentation. A 6-degrees-of-freedom navigation device was designed and fabricated to enable exploration of the 3D space in a manner intuitive to those comfortable with the use of a surgical microscope. Standard haptic devices were also incorporated to assist in navigation and exploration.
Our visualization workstation could be adapted to allow for the effective exploration of middle-ear micro-CT datasets. Functionally significant anatomical details could be recognized and objective data could be extracted.
We have developed an intuitive, rapid, and effective means of exploring otological micro-CT datasets. This system may provide a foundation for additional work based on middle-ear anatomical data.
中耳解剖结构与其正常功能和对疾病过程的反应密切相关。微计算机断层扫描（micro-CT）成像提供了一种以相对快速且无损的方式获取高分辨率解剖数据的机会。然而，为了最佳地提取与功能相关的详细信息，需要一种直观的方法来重建和交互这些数据。
使用微计算机断层扫描（micro-CT）扫描仪获取新鲜离体人颞骨的高分辨率扫描。一种先进的体积渲染器被改编，以实现这些体积数据集的实时重建、显示和操作。一个定制的用户界面提供半自动阈值分割。设计并制造了一个六自由度导航设备，以一种对那些习惯使用手术显微镜的人来说直观的方式，实现对 3D 空间的探索。还集成了标准触觉设备，以协助导航和探索。
我们的可视化工作站可以进行调整，以允许有效地探索中耳 micro-CT 数据集。可以识别出具有重要功能的解剖细节，并提取客观数据。
我们已经开发出一种直观、快速且有效的探索耳科学 micro-CT 数据集的方法。该系统可能为基于中耳解剖数据的进一步工作提供基础。
