Department of Biology of Physical Activity, Neuromuscular Research Center, University of Jyväskylä, PO Box 35, 40014 Jyväskylä, Finland.
Eur J Appl Physiol. 2010 May;109(2):343-53. doi: 10.1007/s00421-010-1360-7. Epub 2010 Jan 26.
This study investigated, in a multi-experiment design, the acute effects of milk protein ingestion, aging [50 young (approximately 26 years) vs. 45 older (approximately 61 years) men] and training state for the blood leukocyte and platelet responses acutely after a single bout of resistance exercise (RE). Moreover, basal effects of 21 weeks of resistance training (RT) were examined. The single bout of RE rapidly increased all blood leukocytes and platelets (P < 0.05). Protein ingestion before or before and after the RE bout did not have an effect on this response. However, younger men had a larger immediate exercise-induced response in leukocytes and platelets than older men. Basal fasting levels of leukocytes and platelets remained unchanged after 21 weeks of RT and this RT period did not change the acute RE-induced leukocyte and platelet response. The long-term RT was, however, able to slightly increase blood hematocrit. Blood platelet counts were consistently higher in the younger men when compared to the older men. Blood lymphopenia occurred only after a larger volume of exercise. In conclusion, the acute increase in blood leukocytes and platelets may be smaller in the older as when compared to the younger men. However, the number of immune cells and thus probably their function may not be affected by milk protein ingestion or months of resistance training.
本研究采用多实验设计，探究了牛奶蛋白摄入、衰老[50 名年轻（约 26 岁）和 45 名年老（约 61 岁）男性]和训练状态对单次抗阻运动（RE）后血液白细胞和血小板反应的急性影响。此外，还检查了 21 周抗阻训练（RT）的基础影响。单次 RE 迅速增加了所有血液白细胞和血小板（P < 0.05）。RE 前后或前后摄入蛋白质对这种反应没有影响。然而，年轻男性的白细胞和血小板即时运动诱导反应大于老年男性。经过 21 周 RT 后，白细胞和血小板的基础空腹水平保持不变，而 RT 期间不会改变白细胞和血小板的急性 RE 诱导反应。然而，长期 RT 能够略微增加血液红细胞比容。与老年男性相比，年轻男性的血小板计数始终较高。只有在进行更大运动量的运动后才会出现血液淋巴细胞减少症。总之，与年轻男性相比，老年男性血液白细胞和血小板的急性增加可能较小。然而，免疫细胞的数量，因此其功能可能不会受到牛奶蛋白摄入或数月抗阻训练的影响。
