来自块根马利筋地上部分的8,12;8,20 - 二环氧 - 8,14 - 断孕甾烷糖苷。

8,12;8,20-Diepoxy-8,14-secopregnane glycosides from the aerial parts of Asclepias tuberosa.

作者信息

Warashina Tsutomu, Noro Tadataka

机构信息

Institute for Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.

出版信息

Chem Pharm Bull (Tokyo). 2010 Feb;58(2):172-9. doi: 10.1248/cpb.58.172.

DOI:10.1248/cpb.58.172

PMID:20118575

Abstract

Further study of constituents from the aerial parts of Asclepias tuberosa afforded twenty-two new steroidal glycosides along with tuberoside B(5) and G(5). These glycosides were confirmed to contain 8,12;8,20-diepoxy-8,14-secopregnanes, tuberogenin and its congeners, as their aglycones. The structure of each of these compounds was elucidated based on the interpretation of NMR and MS measurements and from chemical evidence.

摘要

对块根马利筋地上部分成分的进一步研究得到了22种新的甾体糖苷以及块根糖苷B(5)和G(5)。这些糖苷被证实含有8,12;8,20-二环氧-8,14-裂孕甾烷、块根皂苷元和其同系物作为它们的苷元。基于核磁共振（NMR）和质谱（MS）测量结果的解释以及化学证据阐明了这些化合物各自的结构。