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补充肌酸对改善衰老骨骼健康的潜力。

Potential of creatine supplementation for improving aging bone health.

机构信息

Faculty of Kinesiology & Health Studies, University of Regina, Regina, Saskatchewan, Canada.

出版信息

J Nutr Health Aging. 2010 Feb;14(2):149-53. doi: 10.1007/s12603-009-0224-5.

DOI:10.1007/s12603-009-0224-5
PMID:20126964
Abstract

Aging subsequently results in bone and muscle loss which has a negative effect on strength, agility, and balance leading to increased risks of falls, injuries, and fractures. Resistance training is an effective strategy for maintaining bone mass, possibly by increasing activity of cells involved in bone formation and reducing activity of cells involved in bone resorption. However, bone loss is still evident in older adults who have maintained resistance training for most of their life, suggesting that other factors such as nutrition may be involved in the aging bone process. Emerging evidence suggests that creatine supplementation, with and without resistance training, has the potential to influence bone biology. However, research investigating the longer-term effects of creatine supplementation and resistance training on aging bone is limited.

摘要

随着年龄的增长,人体会出现骨骼和肌肉流失的情况,这会对力量、敏捷性和平衡能力产生负面影响,从而增加跌倒、受伤和骨折的风险。阻力训练是维持骨量的有效策略,可能通过增加参与骨形成的细胞活性和减少参与骨吸收的细胞活性来实现。然而,对于那些一生中大部分时间都坚持进行阻力训练的老年人来说,骨质仍然会流失,这表明其他因素,如营养,可能也参与了衰老过程中的骨骼变化。新出现的证据表明,肌酸补充剂,无论是否与阻力训练结合,都有可能影响骨骼生物学。然而,关于肌酸补充剂和阻力训练对衰老骨骼的长期影响的研究是有限的。

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Strength training preserves the bone mineral density of postmenopausal women without hormone replacement therapy.力量训练可在不进行激素替代疗法的情况下维持绝经后女性的骨密度。
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Protein-containing nutrient supplementation following strength training enhances the effect on muscle mass, strength, and bone formation in postmenopausal women.力量训练后补充含蛋白质的营养物质可增强对绝经后女性肌肉量、力量和骨形成的影响。
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