RE ARTU Research Laboratories, John Paul II Centre For High Technology Research and Education in Biomedical Sciences, Catholic University, Largo Gemelli 1, 86100, Campobasso, Italy.
Intern Emerg Med. 2010 Aug;5(4):291-7. doi: 10.1007/s11739-010-0346-0. Epub 2010 Feb 3.
An inverse association between moderate alcohol intake and cardiovascular risk, in particular coronary disease and ischemic stroke, has been shown in many epidemiologic studies. In addition, several other diseases are also known to occur less frequently in moderate drinkers than in non-drinkers, whereas excess of drinking is invariably harmful. However, some concern has been recently raised about the possibility that at all dosages the harm of alcohol could overcome its beneficial effects. We present here the epidemiologic and mechanistic evidence to support the protective effect of moderate alcohol intake against cardiovascular disease and all-cause mortality.
许多流行病学研究表明，适量饮酒与心血管风险（特别是冠心病和缺血性卒中）呈负相关。此外，适量饮酒者患某些疾病的频率也低于不饮酒者，而过量饮酒总是有害的。然而，最近人们开始担心，无论剂量如何，酒精的危害都可能超过其有益作用。在这里，我们提出了流行病学和机制证据，以支持适量饮酒对心血管疾病和全因死亡率的保护作用。
