用移动磁阱操控标记和未标记的磁性细胞。
Manipulation of magnetically labeled and unlabeled cells with mobile magnetic traps.
机构信息
Department of Physics, The Ohio State University, Columbus, Ohio, USA.
出版信息
Biophys J. 2010 Feb 3;98(3):412-7. doi: 10.1016/j.bpj.2009.10.036.
Abstract
A platform of discrete microscopic magnetic elements patterned on a surface offers dynamic control over the motion of fluid-borne cells by reprogramming the magnetization within the magnetic bits. T-lymphocyte cells tethered to magnetic microspheres and untethered leukemia cells are remotely manipulated and guided along desired trajectories on a silicon surface by directed forces with average speeds up to 20 microm/s. In addition to navigating cells, the microspheres can be operated from a distance to push biological and inert entities and act as local probes in fluidic environments.
摘要
在表面上制作离散微观磁性元件的平台通过重新编程磁位中的磁化来提供对流体载体细胞运动的动态控制。通过定向力将与磁性微球连接的 T 淋巴细胞和未连接的白血病细胞远程操纵并沿着硅表面的期望轨迹引导，平均速度高达 20 微米/秒。除了引导细胞之外，微球还可以远距离操作，推动生物和惰性实体，并在流体环境中充当局部探针。
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本文引用的文献
1
Observation of a single-beam gradient force optical trap for dielectric particles.介电粒子单光束梯度力光阱的观测。
Opt Lett. 1986 May 1;11(5):288. doi: 10.1364/ol.11.000288.
2
Optimization of an enrichment process for circulating tumor cells from the blood of head and neck cancer patients through depletion of normal cells.通过去除正常细胞优化从头颈癌患者血液中富集循环肿瘤细胞的过程。
Biotechnol Bioeng. 2009 Feb 1;102(2):521-34. doi: 10.1002/bit.22066.
3
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy.单分子力谱学：光镊、磁镊和原子力显微镜。
Nat Methods. 2008 Jun;5(6):491-505. doi: 10.1038/nmeth.1218.
4
A novel high throughput immunomagnetic cell sorting system for potential clinical scale depletion of T cells for allogeneic stem cell transplantation.一种新型高通量免疫磁珠细胞分选系统，用于异基因干细胞移植中T细胞的潜在临床规模清除。
Exp Hematol. 2007 Oct;35(10):1613-22. doi: 10.1016/j.exphem.2007.06.015. Epub 2007 Aug 13.
5
Localized and delocalized motion of colloidal particles on a magnetic bubble lattice.胶体粒子在磁泡晶格上的局域运动和非局域运动。
Phys Rev Lett. 2007 Jul 20;99(3):038303. doi: 10.1103/PhysRevLett.99.038303.
6
Acute hydrodynamic forces and apoptosis: a complex question.急性流体动力与细胞凋亡：一个复杂的问题。
Biotechnol Bioeng. 2007 Nov 1;98(4):772-88. doi: 10.1002/bit.21476.
7
Magnetism and microfluidics.磁性与微流体技术。
Lab Chip. 2006 Jan;6(1):24-38. doi: 10.1039/b513005k. Epub 2005 Nov 28.
8
Arranging matter by magnetic nanoparticle assemblers.通过磁性纳米颗粒组装器排列物质。
Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8860-4. doi: 10.1073/pnas.0500409102. Epub 2005 Jun 13.
9
Capillary electrophoresis of biological particles: viruses, bacteria, and eukaryotic cells.
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10
A revolution in optical manipulation.光学操控领域的一场革命。
Nature. 2003 Aug 14;424(6950):810-6. doi: 10.1038/nature01935.
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