Webel Allison R
Case Western Reserve University, Cleveland, OH, USA.
AIDS Care. 2010 Sep;22(9):1029-40. doi: 10.1080/09540120903214389.
To test the impact of participation in a peer-based intervention for symptom management for women living with HIV infection on selected outcome measures including, symptom intensity, medication adherence, viral control, and quality of life.
Randomized clinical trial.
Participants were recruited using a convenient, consecutive sampling method. Those participants randomized to the experimental condition attended seven, peer-led sessions over seven weeks. Participants randomized to the control condition received a copy of HIV Symptom Management Strategies: A Manual for People Living with HIV/AIDS. Participants completed four surveys assessing change over time in the aforementioned outcome variables.
Eighty-nine HIV-infected women followed over 14 weeks and there were no differences between the two groups on baseline demographic variables. Mixed-effects regression indicated no significant difference between groups across time in total symptom intensity score and medication adherence. There was a significant difference between groups across time for two of the nine quality of life scales - HIV Mastery (chi(2)=25.08; p<0.005) and Disclosure Worries (chi(2)=24.67; p<0.005).
In urban-dwelling women living with HIV/AIDS, results suggest that a peer-based symptom management intervention may not decrease symptom intensity or increase medication adherence. There is positive evidence that suggests that the intervention may increase some important aspects of quality of life. However, further research is warranted to elucidate the effect of peer-based interventions in achieving positive self-management outcomes.
测试参与一项针对感染艾滋病毒女性的同伴支持症状管理干预措施对选定的结果指标的影响,这些指标包括症状强度、药物依从性、病毒控制和生活质量。
随机临床试验。
采用方便的连续抽样方法招募参与者。那些被随机分配到实验条件组的参与者在七周内参加了七次由同伴主导的课程。被随机分配到对照组的参与者收到了一份《艾滋病毒症状管理策略:艾滋病毒/艾滋病感染者手册》。参与者完成了四项调查,评估上述结果变量随时间的变化。
对89名感染艾滋病毒的女性进行了为期14周的跟踪调查,两组在基线人口统计学变量上没有差异。混合效应回归表明,两组在总症状强度评分和药物依从性方面随时间没有显著差异。在九个生活质量量表中的两个量表上,两组随时间存在显著差异——艾滋病毒掌控感(χ² = 25.08;p < 0.005)和披露担忧(χ² = 24.67;p < 0.005)。
对于城市中感染艾滋病毒/艾滋病的女性,结果表明基于同伴的症状管理干预可能不会降低症状强度或提高药物依从性。有积极证据表明该干预可能会提高生活质量的一些重要方面。然而,需要进一步研究以阐明基于同伴的干预在实现积极自我管理结果方面的效果。