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Dehydration inhibits matrix synthesis and cell proliferation. An in vitro study of rabbit flexor tendons.

作者信息

Abrahamsson S O, Lohmander L S, Lundborg G

机构信息

Lund University, Department of Hand Surgery, Malmö, Sweden.

出版信息

Acta Orthop Scand. 1991 Apr;62(2):159-62. doi: 10.3109/17453679108999247.

DOI:10.3109/17453679108999247
PMID:2014727
Abstract

Segments of the deep flexor tendon of the rabbit were exposed to air; the effects of dehydration on in vitro synthesis of proteoglycan, collagen, noncollagenous protein, and cell proliferation were compared with tendon segments that were kept moist with physiologic saline. After 20 min of exposure to air, the tendons lost half and after 40 min all of their ability to synthesize matrix components and to proliferate, whereas irrigated tendons remained viable during the entire experiment.

摘要

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