Hanff G, Abrahamsson S O
Department of Hand Surgery, University Hospital, Malmö, Sweden.
J Hand Surg Br. 1996 Jun;21(3):419-23. doi: 10.1016/s0266-7681(05)80222-0.
The biological adaptation and integration of flexor tendon pulleys reconstructed with expanded polytetrafluorethylene (e-PTFE) were investigated 3 months after operation. E-PTFE pulleys showed no signs of failure, adverse tissue reactions or detrimental effects on the surface of underlying tendons. Cells in pulleys reconstructed with e-PTFE synthesized proteoglycan, collagen and non-collagen protein at a higher rate, and DNA at a lower rate, than cells in sham operated pulleys. Cells in pulleys reconstructed with e-PTFE synthesized proteoglycan at a lower rate, and protein at a higher rate, than cells in e-PTFE strips placed subcutaneously. Flexor tendon segments underlying reconstructed or sham operated pulleys synthesized matrix components and DNA at comparable rates.
术后3个月对用膨体聚四氟乙烯（e-PTFE）重建的屈肌腱滑车的生物学适应性和整合情况进行了研究。e-PTFE滑车未出现失败迹象、不良组织反应或对其下方肌腱表面的有害影响。与假手术滑车中的细胞相比，用e-PTFE重建的滑车中的细胞合成蛋白聚糖、胶原蛋白和非胶原蛋白的速率更高，而合成DNA的速率更低。与皮下放置的e-PTFE条带中的细胞相比，用e-PTFE重建的滑车中的细胞合成蛋白聚糖的速率更低，而合成蛋白质的速率更高。重建滑车或假手术滑车下方的屈肌腱节段合成基质成分和DNA的速率相当。
