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皮下之见:从生物学和社会科学理论出发,探索黑-白人群健康差距背后的机制

Under the skin: using theories from biology and the social sciences to explore the mechanisms behind the black-white health gap.

机构信息

Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, USA.

出版信息

Am J Public Health. 2010 Apr 1;100 Suppl 1(Suppl 1):S36-40. doi: 10.2105/AJPH.2009.171140. Epub 2010 Feb 10.

DOI:10.2105/AJPH.2009.171140
PMID:20147678
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2837427/
Abstract

Equity and social well-being considerations make Black-White health disparities an area of important concern. Although previous research suggests that discrimination- and poverty-related stressors play a role in African American health outcomes, the mechanisms are unclear. Allostatic load is a concept that can be employed to demonstrate how environmental stressors, including psychosocial ones, may lead to a cumulative physiological toll on the body. We discuss both the usefulness of this framework for understanding how discrimination can lead to worse health among African Americans, and the challenges for conceptualizing biological risk with existing data and methods. We also contrast allostatic load with theories of historical trauma such as posttraumatic slavery syndrome. Finally, we offer our suggestions for future interdisciplinary research on health disparities.

摘要

公平和社会福利的考虑使得黑人和白人之间的健康差距成为一个重要的关注点。尽管之前的研究表明,与歧视和贫困相关的压力源在非裔美国人的健康结果中起着一定的作用,但其中的机制尚不清楚。适应负荷是一个可以用来解释环境压力源(包括心理社会压力源)如何导致身体累积的生理损耗的概念。我们讨论了这个框架对于理解歧视如何导致非裔美国人健康状况恶化的有用性,以及在现有数据和方法下对生物风险进行概念化的挑战。我们还将适应负荷与创伤后奴隶制综合征等历史创伤理论进行了对比。最后,我们为健康差异的未来跨学科研究提供了建议。

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本文引用的文献

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Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention.神经科学、分子生物学与健康差距的童年根源:构建健康促进与疾病预防的新框架
JAMA. 2009 Jun 3;301(21):2252-9. doi: 10.1001/jama.2009.754.
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Neighborhoods and cumulative biological risk profiles by race/ethnicity in a national sample of U.S. adults: NHANES III.美国成年人全国样本中按种族/族裔划分的社区与累积生物风险概况:第三次美国国家健康与营养检查调查(NHANES III)
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Discrimination and racial disparities in health: evidence and needed research.健康方面的歧视与种族差异:证据及所需研究。
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Should health studies measure wealth? A systematic review.健康研究应该衡量财富吗?一项系统综述。
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PTSD and stress sensitisation: a tale of brain and body Part 2: animal models.创伤后应激障碍与应激敏化:大脑与身体的故事 第二部分:动物模型
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The mental health of Black Caribbean immigrants: results from the National Survey of American Life.加勒比黑人移民的心理健康:美国生活全国调查结果
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The National Children's Study: a 21-year prospective study of 100,000 American children.全国儿童研究:对10万名美国儿童进行的为期21年的前瞻性研究。
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