Department of Dermatology, University of Wisconsin, Madison, Wisconsin 53706, USA.
Nutr Cancer. 2009;61(6):836-41. doi: 10.1080/01635580903285056.
The prevention of prostate cancer (PCa) is a crucial medical challenge in developed countries. PCa remains surrounded by puzzles in spite of the considerable progress in research, diagnosis, and treatment. It is an ideal target for chemoprevention, as clinically significant PCa usually requires more than two decades for development. Green tea and its major constituent epigallocatechin gallate (EGCG) have been extensively studied as a potential treatment for a variety of diseases including cancer. In this review, we highlight the evidences of green tea polyphenols from preclinical and clinical studies in the chemoprevention/chemotherapy of PCa.
预防前列腺癌（PCa）是发达国家面临的一项重要医学挑战。尽管在研究、诊断和治疗方面取得了相当大的进展，但 PCa 仍然存在许多未解之谜。由于临床上有意义的 PCa 通常需要超过二十年的时间才能发展，因此它是化学预防的理想目标。绿茶及其主要成分表没食子儿茶素没食子酸酯（EGCG）已被广泛研究作为治疗多种疾病（包括癌症）的潜在药物。在这篇综述中，我们强调了来自临床前和临床研究的绿茶多酚在 PCa 的化学预防/化疗中的证据。
