Suppr超能文献

奶酪乳清超滤渗透物是乳寡糖的一个来源。

Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides.

作者信息

Barile Daniela, Tao Nannan, Lebrilla Carlito B, Coisson Jean-Daniel, Arlorio Marco, German J Bruce

机构信息

Department of Food Science and Technology, University of California, Davis, CA 95616, USA.

出版信息

Int Dairy J. 2009 Sep 1;19(9):524-530. doi: 10.1016/j.idairyj.2009.03.008.

DOI:10.1016/j.idairyj.2009.03.008
PMID:20161544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2805004/
Abstract

Previously undescribed oligosaccharides in bovine cheese whey permeate were characterized by a combination of nanoelectrospray Fourier Transform Ion Cyclotron Resonance (nESI-FTICR) mass spectrometry and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry. Oligosaccharide composition was elucidated by collision-induced dissociation within the ICR cell. In addition to sialyllactose (the most abundant oligosaccharide in bovine colostrum), we identified 14 other oligosaccharides, half of which have the same composition of human milk oligosaccharides. These oligosaccharides could potentially be used as additives in infant formula and products for the pharmaceutical industry. Because whey permeate is a by-product from the production of whey protein concentrate (WPC) and is readily available, it is an attractive source of oligosaccharides for potential application in human nutrition.

摘要

通过纳米电喷雾傅里叶变换离子回旋共振（nESI-FTICR）质谱和基质辅助激光解吸/电离傅里叶变换离子回旋共振（MALDI-FTICR）质谱相结合的方法，对牛乳清渗透液中以前未描述的低聚糖进行了表征。通过在ICR细胞内的碰撞诱导解离来阐明低聚糖的组成。除了唾液乳糖（牛乳初乳中最丰富的低聚糖）外，我们还鉴定出了其他14种低聚糖，其中一半与人乳低聚糖的组成相同。这些低聚糖有可能用作婴儿配方奶粉和制药行业产品中的添加剂。由于乳清渗透液是生产乳清蛋白浓缩物（WPC）的副产品，且易于获得，因此它是一种有吸引力的低聚糖来源，有可能应用于人类营养领域。

相似文献

1
Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides.
Int Dairy J. 2009 Sep 1;19(9):524-530. doi: 10.1016/j.idairyj.2009.03.008.
2
Comprehensive peptidomic and glycomic evaluation reveals that sweet whey permeate from colostrum is a source of milk protein-derived peptides and oligosaccharides.
Food Res Int. 2014 Sep 1;63(Pt B):203-209. doi: 10.1016/j.foodres.2014.03.021.
3
Rapid Screening of Bovine Milk Oligosaccharides in a Whey Permeate Product and Domestic Animal Milks by Accurate Mass Database and Tandem Mass Spectral Library.
J Agric Food Chem. 2016 Aug 17;64(32):6364-74. doi: 10.1021/acs.jafc.6b02039. Epub 2016 Aug 8.
4
Discovery of Novel High-Molecular Weight Oligosaccharides Containing N-Acetylhexosamine in Bovine Colostrum Whey Permeate Hydrolyzed with Aspergillus oryzae β-Galactosidase.
J Agric Food Chem. 2019 Mar 27;67(12):3313-3322. doi: 10.1021/acs.jafc.8b06965. Epub 2019 Mar 14.
5
Role of pH in the recovery of bovine milk oligosaccharides from colostrum whey permeate by nanofiltration.
Int Dairy J. 2017 Mar;66:68-75. doi: 10.1016/j.idairyj.2016.10.016. Epub 2016 Nov 21.
6
Mass spectrometric detection of multiple extended series of neutral highly fucosylated -acetyllactosamine oligosaccharides in human milk.
Int J Mass Spectrom. 2008 Dec 1;278(2-3):129-136. doi: 10.1016/j.ijms.2008.09.005. Epub 2008 Sep 16.
7
Methods for the quantitation of human milk oligosaccharides in bacterial fermentation by mass spectrometry.
Anal Biochem. 2007 Feb 1;361(1):15-23. doi: 10.1016/j.ab.2006.11.010. Epub 2006 Nov 27.
8
Novel high-molecular weight fucosylated milk oligosaccharides identified in dairy streams.
PLoS One. 2014 May 8;9(5):e96040. doi: 10.1371/journal.pone.0096040. eCollection 2014.
9
Comparative study of the oligosaccharide profile in goat, bovine, sheep, and human milk whey.
Food Chem. 2025 Jan 15;463(Pt 1):141123. doi: 10.1016/j.foodchem.2024.141123. Epub 2024 Sep 4.
10
Electrospray ionization and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry of permethylated oligosaccharides.
Anal Chem. 1998 Mar 1;70(5):857-64. doi: 10.1021/ac970562+.

引用本文的文献

1
Human Milk Oligosaccharides: Decoding Their Structural Variability, Health Benefits, and the Evolution of Infant Nutrition.
Nutrients. 2024 Dec 30;17(1):118. doi: 10.3390/nu17010118.
2
Upcycling Milk Industry Byproducts into Larvae: Investigation on Fat, Protein, and Sugar Composition.
Foods. 2024 Oct 29;13(21):3450. doi: 10.3390/foods13213450.
3
Dietary supplementation of 3'-sialyllactose or 6'-sialyllactose elicits minimal influence on cognitive and brain development in growing pigs.
Front Behav Neurosci. 2024 Jan 10;17:1337897. doi: 10.3389/fnbeh.2023.1337897. eCollection 2023.
4
Creation of a milk oligosaccharide database, MilkOligoDB, reveals common structural motifs and extensive diversity across mammals.
Sci Rep. 2023 Jun 26;13(1):10345. doi: 10.1038/s41598-023-36866-y.
5
Spray-Dried Microcapsules of Cheese Whey and Whey Permeate as a Strategy to Protect Chia Oil from Oxidative Degradation.
Food Technol Biotechnol. 2022 Dec;60(4):449-457. doi: 10.17113/ftb.60.04.22.7451.
6
Role of milk carbohydrates in intestinal health of nursery pigs: a review.
J Anim Sci Biotechnol. 2022 Jan 5;13(1):6. doi: 10.1186/s40104-021-00650-7.
7
Bioactives in bovine milk: chemistry, technology, and applications.
Nutr Rev. 2021 Dec 8;79(Suppl 2):48-69. doi: 10.1093/nutrit/nuab099.
8
Term infant formula supplemented with milk-derived oligosaccharides shifts the gut microbiota closer to that of human milk-fed infants and improves intestinal immune defense: a randomized controlled trial.
Am J Clin Nutr. 2022 Jan 11;115(1):142-153. doi: 10.1093/ajcn/nqab336.
9
Human Milk Oligosaccharide-Stimulated Species Contribute to Prevent Later Respiratory Tract Infections.
Microorganisms. 2021 Sep 12;9(9):1939. doi: 10.3390/microorganisms9091939.
10
Bovine Milk Oligosaccharides and Human Milk Oligosaccharides Modulate the Gut Microbiota Composition and Volatile Fatty Acid Concentrations in a Preclinical Neonatal Model.
Microorganisms. 2021 Apr 21;9(5):884. doi: 10.3390/microorganisms9050884.

本文引用的文献

1
Nondigestible Oligo- and Polysaccharides (Dietary Fiber): Their Physiology and Role in Human Health and Food.
Compr Rev Food Sci Food Saf. 2002 Oct;1(3):90-109. doi: 10.1111/j.1541-4337.2002.tb00009.x.
2
Bovine milk glycome.
J Dairy Sci. 2008 Oct;91(10):3768-78. doi: 10.3168/jds.2008-1305.
3
Oligosaccharides from milk.
J Nutr. 2007 Mar;137(3 Suppl 2):847S-9S. doi: 10.1093/jn/137.3.847S.
4
Process development for the production of prebiotic galacto-oligosaccharides from lactose using beta-galactosidase from Lactobacillus sp.
Biotechnol J. 2007 Apr;2(4):480-5. doi: 10.1002/biot.200600230.
5
Prebiotics in human milk: a review.
Dig Liver Dis. 2006 Dec;38 Suppl 2:S291-4. doi: 10.1016/S1590-8658(07)60013-9.
6
A strategy for annotating the human milk glycome.
J Agric Food Chem. 2006 Oct 4;54(20):7471-80. doi: 10.1021/jf0615810.
7
Distribution of sialic acids in the milk of spanish mothers of full term infants during lactation.
J Pediatr Gastroenterol Nutr. 2004 Nov;39(5):499-503. doi: 10.1097/00005176-200411000-00010.
8
Application of Fourier transform ion cyclotron resonance mass spectrometry to oligosaccharides.
Mass Spectrom Rev. 2005 Mar-Apr;24(2):232-64. doi: 10.1002/mas.20010.
9
Activation of large ions in FT-ICR mass spectrometry.
Mass Spectrom Rev. 2005 Mar-Apr;24(2):135-67. doi: 10.1002/mas.20012.
10
The first prebiotics in humans: human milk oligosaccharides.
J Clin Gastroenterol. 2004 Jul;38(6 Suppl):S80-3. doi: 10.1097/01.mcg.0000128926.14285.25.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验