通过串联分子内迈克尔环化-HWE烯化反应合成（±）-油橄榄苦素
Synthesis of (+/-)-Oleocanthal via a Tandem Intramolecular Michael Cyclization-HWE Olefination.
作者信息
English Brandon J, Williams Robert M
机构信息
Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
出版信息
Tetrahedron Lett. 2009 Jun 10;50(23):2713. doi: 10.1016/j.tetlet.2009.03.145.
Abstract
A synthesis of racemic oleocanthal has been accomplished in eleven steps from 1,3 propanediol by a key tandem intramolecular Michael cyclization-Horner Wadsworth Emmons olefination.
摘要
通过关键的分子内迈克尔环化-霍纳尔-沃兹沃思-埃蒙斯烯烃化反应，从1,3-丙二醇出发，经十一步反应完成了外消旋油橄榄苦素的合成。
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