Marwaha Steven, Johnson Sonia, Bebbington Paul E, Angermeyer Matthias C, Brugha Traolach S, Azorin Jean-Michel, Killian Reinhold, Hansen Karina, Toumi Mondher
Health Sciences Research Institute, Warwick Medical School and Research Department of Mental Health Sciences, University College London, London, United Kingdom.
Epidemiol Psichiatr Soc. 2009 Oct-Dec;18(4):344-51.
To examine the associations of job acquisition and loss in a representative, prospective community sample of people with schizophrenia living in the UK, France and Germany.
A representative sample of twelve hundred and eight people with schizophrenia were recruited from selected secondary mental health services in the U.K, France and Germany and followed up for 2 years. Information on demographic details, psychotic symptoms and work status was collected.
The odds of getting jobs were increased by being resident in Marseille, Leipzig, Hemer and Heilbronn and by a higher regional general population employment rate. The odds were reduced by living in Lyon, a later illness onset, a longer length of illness, a continuous illness course and more severe negative psychotic symptoms. Previous vocational training reduced the odds of losing employment, whilst living in Lyon or Leipzig, harmful use of alcohol and more positive psychotic symptoms at baseline all increased the odds.
In addition to illness related factors, area of residence and local labour market conditions appear to be important in explaining employment status change in people with schizophrenia.
在英国、法国和德国具有代表性的精神分裂症患者前瞻性社区样本中，研究就业获得与失业的相关性。
从英国、法国和德国选定的二级精神卫生服务机构招募了1208名精神分裂症患者的代表性样本，并随访2年。收集了人口统计学细节、精神病症状和工作状况的信息。
居住在马赛、莱比锡、黑默尔和海尔布隆以及地区总体人口就业率较高会增加就业几率。居住在里昂、发病较晚、病程较长、疾病呈持续状态以及阴性精神病症状较严重会降低就业几率。以前的职业培训降低了失业几率，而居住在里昂或莱比锡、酒精有害使用以及基线时更多的阳性精神病症状都会增加失业几率。
除了与疾病相关的因素外，居住地区和当地劳动力市场状况在解释精神分裂症患者就业状况变化方面似乎很重要。
