Ahmad Misbah, Hussain Amjad, Muhammad Wazir, Rizvi Syed Qaisar Abbas
Institute of Nuclear Medicine Oncology and Radiotherapy (INOR), Abbottabad; Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan.
J Med Phys. 2010 Jan;35(1):33-41. doi: 10.4103/0971-6203.57116.
This study was designed to investigate variation in Varian's Physical and Enhanced Dynamic Wedge Factors (WF) as a function of depth and field size. The profiles for physical wedges (PWs) and enhanced dynamic wedges (EDWs) were also measured using LDA-99 array and compared for confirmation of EDW angles at different depths and field sizes. WF measurements were performed in water phantom using cylindrical 0.66 cc ionization chamber. WF was measured by taking the ratio of wedge and open field ionization data. A normalized wedge factor (NWF) was introduced to circumvent large differences between wedge factors for different wedge angles. A strong linear dependence of PW Factor (PWF) with depth was observed. Maximum variation of 8.9% and 4.1% was observed for 60 degrees PW with depth at 6 and 15 MV beams respectively. The variation in EDW Factor (EDWF) with depth was almost negligible and less than two per cent. The highest variation in PWF as a function of field size was 4.1% and 3.4% for thicker wedge (60 degrees ) at 6 and 15 MV beams respectively and decreases with decreasing wedge angle. EDWF shows strong field size dependence and significant variation was observed for all wedges at both photon energies. Differences in profiles between PW and EDW were observed on toe and heel sides. These differences were dominant for larger fields, shallow depths, thicker wedges and low energy beam. The study indicated that ignoring depth and field size dependence of WF may result in under/over dose to the patient especially doing manual point dose calculation.
本研究旨在调查瓦里安公司的物理楔形因子和增强动态楔形因子(WF)随深度和射野大小的变化情况。还使用LDA - 99阵列测量了物理楔形(PW)和增强动态楔形(EDW)的剂量分布,并进行比较,以确认不同深度和射野大小下EDW的角度。WF测量是在水模体中使用圆柱形0.66 cc电离室进行的。通过获取楔形野和开放野电离数据的比值来测量WF。引入了归一化楔形因子(NWF)以规避不同楔形角度的楔形因子之间的巨大差异。观察到PW因子(PWF)与深度有很强的线性相关性。对于60度的PW,在6 MV和15 MV射束下,随深度的最大变化分别为8.9%和4.1%。EDW因子(EDWF)随深度的变化几乎可以忽略不计,小于2%。PWF随射野大小变化的最大值,对于较厚的楔形(60度),在6 MV和15 MV射束下分别为4.1%和3.4%,并且随楔形角度减小而降低。EDWF显示出很强的射野大小依赖性,在两种光子能量下,所有楔形均观察到显著变化。在趾侧和跟侧观察到PW和EDW的剂量分布存在差异。这些差异在大射野(较大的射野尺寸)、浅深度、厚楔形和低能量射束情况下更为明显。该研究表明,忽略WF对深度和射野大小的依赖性可能导致对患者的剂量不足或过量,尤其是在进行手动点剂量计算时。