Njeh Christopher F
Marshfield Clinic.
J Appl Clin Med Phys. 2015 Sep 8;16(5):271–283. doi: 10.1120/jacmp.v16i5.5498.
Dose inhomogeneity in treatment planning can be compensated using physical wedges. Enhanced dynamic wedges (EDW) were introduced by Varian to overcome some of the shortcomings of physical wedges. The objectives of this study were to measure EDW output factors for 6 MV and 20 MV photon energies for a Varian 2300CD. Secondly, to review the literature in terms of published enhanced dynamic wedge output factors (EDWOF) for different Varian models and thereby add credence to the case of the validity of reference databases. The enhanced dynamic wedge output factors were measured for the Varian 2300CD for both 6MV and 20 MV photon energies. Twelve papers with published EDWOF for different Varian linac models were found in the literature. Comparing our results with the published mean, we found an excellent agreement for 6 MV EDWOF, with the percentage differences ranging from 0.01% to 0.57%, with a mean of 0.03%. The coefficient of variation of published EDWOF ranged from 0.17% to 0.85% and 0.1% to 0.9% for the for 6 MV and 18 MV photon energies, respectively. This paper provides the first published EDWOF for 20 MV photon energy. In addition, we have provided the first compendium of EDWOFs for different Varian linac models. The consistency of value across models and institution provide further support that a standard dataset of basic photon and electron dosimetry could be established as a guide for future commissioning, beam modeling, and quality assurance purposes.
治疗计划中的剂量不均匀性可以通过物理楔形板来补偿。瓦里安公司推出了增强动态楔形板(EDW)以克服物理楔形板的一些缺点。本研究的目的,一是测量瓦里安2300CD型直线加速器在6MV和20MV光子能量下的增强动态楔形板输出因子;二是回顾关于不同瓦里安型号已发表的增强动态楔形板输出因子(EDWOF)的文献,从而为参考数据库有效性的案例增加可信度。针对瓦里安2300CD型直线加速器,测量了6MV和20MV光子能量下的增强动态楔形板输出因子。在文献中发现了12篇关于不同瓦里安直线加速器型号已发表的EDWOF的论文。将我们的结果与已发表的平均值进行比较,我们发现6MV的EDWOF一致性极佳,百分比差异范围为0.01%至0.57%,平均值为0.03%。已发表的6MV和18MV光子能量的EDWOF的变异系数分别为0.17%至0.85%和0.1%至0.9%。本文首次发表了20MV光子能量下的EDWOF。此外,我们还首次提供了不同瓦里安直线加速器型号的EDWOF汇编。不同型号和机构之间数值的一致性进一步支持了可以建立一个基本光子和电子剂量学标准数据集,作为未来调试、束流建模和质量保证的指南。