Clinical Research Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
J Hum Hypertens. 2010 Dec;24(12):807-13. doi: 10.1038/jhh.2010.18. Epub 2010 Mar 4.
Previous studies reported that a device-guided slow-breathing (DGB) exercise decreases resting blood pressure (BP) in hypertensive patients. This study investigated the effects of daily practice of DGB on (a) 24-h BP and breathing patterns in the natural environment, as well as (b) BP and breathing pattern during clinic rest. Altogether, 40 participants with pre-hypertension or stage 1 hypertension were trained to decrease breathing rate through DGB or to passively attend to breathing (control, CTL) during daily 15-min sessions. The participants practiced their breathing exercise at home for 4 weeks. The DGB (but not the CTL) intervention decreased clinic resting BP, mid-day ambulatory systolic BP (in women only) and resting breathing rate, and increased resting tidal volume. However, 24-h BP level was not changed by DGB or CTL interventions, nor was overnight breathing pattern. These findings are consistent with the conclusion that a short-term, autonomic mechanism mediated the observed changes in resting BP, but provided no evidence that regular DGB affected factors involved in long-term BP regulation. Additional research will be needed to determine whether 24-h BP can be lowered by a more prolonged intervention.
先前的研究报告表明，设备引导的缓慢呼吸（DGB）运动可降低高血压患者的静息血压（BP）。本研究调查了 DGB 日常练习对（a）自然环境下 24 小时血压和呼吸模式，以及（b）诊所休息时血压和呼吸模式的影响。共有 40 名患有前期高血压或 1 期高血压的参与者接受训练，通过 DGB 降低呼吸频率，或在日常 15 分钟的课程中被动关注呼吸（对照组，CTL）。参与者在家中练习呼吸运动 4 周。DGB（而不是 CTL）干预降低了诊所休息时的血压、中午动态收缩压（仅女性）和休息时的呼吸频率，并增加了休息时的潮气量。然而，DGB 或 CTL 干预并未改变 24 小时血压水平，也未改变夜间呼吸模式。这些发现与短期自主机制介导观察到的静息血压变化的结论一致，但没有证据表明定期 DGB 会影响长期血压调节相关因素。需要进一步研究来确定更长期的干预是否可以降低 24 小时血压。
