Department of Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA.
Health Qual Life Outcomes. 2010 Mar 11;8:26. doi: 10.1186/1477-7525-8-26.
It is arguable that modification of diet, given its potential for positive health outcomes, should be widely advocated and adopted. However, food intake, as a basic human need, and its modification may be accompanied by sensations of both pleasure and despondency and may consequently affect to quality of life (QoL). Thus, the feasibility and success of dietary changes will depend, at least partly, on whether potential negative influences on QoL can be avoided. This is of particular importance in the context of dietary intervention studies and in the development of new food products to improve health and well being. Instruments to measure the impact of nutrition on quality of life in the general population, however, are few and far between. Therefore, the aim of this project was to develop an instrument for measuring QoL related to nutrition in the general population.
We recruited participants from the general population and followed standard methodology for quality of life instrument development (identification of population, item selection, n = 24; item reduction, n = 81; item presentation, n = 12; pretesting of questionnaire and initial validation, n = 2576; construct validation n = 128; and test-retest reliability n = 20). Of 187 initial items, 29 were selected for final presentation. Factor analysis revealed an instrument with 5 domains. The instrument demonstrated good cross-sectional divergent and convergent construct validity when correlated with scores of the 8 domains of the SF-36 (ranging from -0.078 to 0.562, 19 out of 40 tested correlations were statistically significant and 24 correlations were predicted correctly) and good test-retest reliability (intra-class correlation coefficients from 0.71 for symptoms to 0.90).
We developed and validated an instrument with 29 items across 5 domains to assess quality of life related to nutrition and other aspects of food intake. The instrument demonstrated good face and construct validity as well as good reliability. Future work will focus on the evaluation of longitudinal construct validity and responsiveness.
饮食的改变可能会对健康产生积极影响，因此应该广泛提倡和采用。然而，作为人类的基本需求之一，食物的摄入及其改变可能会带来愉悦和沮丧感，从而影响生活质量（QoL）。因此，饮食改变的可行性和成功与否至少在一定程度上取决于是否可以避免对 QoL 的潜在负面影响。这在饮食干预研究和开发新的食品产品以改善健康和幸福感方面尤为重要。然而，用于衡量一般人群营养对生活质量影响的工具却很少。因此，本项目的目的是开发一种用于衡量一般人群营养相关生活质量的工具。
我们从一般人群中招募参与者，并遵循质量生活工具开发的标准方法（确定人群、项目选择、n = 24；项目减少、n = 81；项目展示、n = 12；问卷预测试和初步验证、n = 2576；结构验证、n = 128；测试 - 重测信度、n = 20）。在 187 个初始项目中，选择了 29 个项目进行最终展示。因子分析显示，该工具具有 5 个领域。当与 SF-36 的 8 个领域的分数相关联时，该工具表现出良好的横向发散和收敛结构有效性（相关系数范围为 -0.078 至 0.562，40 个测试相关性中有 19 个具有统计学意义，24 个相关性预测正确），并且具有良好的测试 - 重测信度（症状的组内相关系数为 0.71，最高为 0.90）。
我们开发并验证了一种包含 29 个项目和 5 个领域的工具，用于评估与营养和食物摄入其他方面相关的生活质量。该工具具有良好的表面和结构有效性以及良好的可靠性。未来的工作将集中于评估纵向结构有效性和反应性。
